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1,2-Dimethylhydrazine

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  • Name 1,2-Dimethylhydrazine
  • EINECSN/A
  • CAS No. 540-73-8
  • Density0.759g/cm3
  • PSA24.06000
  • LogP0.12200
  • SolubilityN/A
  • Melting Point-8.9°C
  • FormulaC2H8 N2
  • Boiling Point81.5°Cat760mmHg
  • Molecular Weight60.0989
  • Flash Point°C
  • Transport InformationN/A
  • AppearanceN/A
  • SafetyConfirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and intramuscular routes. Moderately toxic by inhalation. Human mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. A high-energy propellant for liquid-fueled rockets. When heated to decomposition it emits toxic fumes of NOx.
  • Risk CodesR45; R23/24/25; R51/53
  • Molecular Structure
    Molecular Structure of 540-73-8 (1,2-Dimethyl hydrazine)
  • Hazard SymbolsT,N
  • SynonymsT,N

1,2-Dimethylhydrazine Chemical Properties

IUPAC  Name: 1,2-Dimethylhydrazine   
Molecular Formula: C2H8N2
Molecular Weight: 60.12
Freely Rotating Bonds: 1
Polar Surface Area: 6.48 Å2
Index of Refraction: 1.383
Molar Refractivity: 18.5 cm3
Molar Volume: 79.1 cm3
Polarizability: 7.33 ×10-24 cm3
Surface Tension: 20 dyne/cm
Density: 0.759 g/cm3
Enthalpy of Vaporization: 32.22 kJ/mol
Boiling Point: 81.5 °C at 760 mmHg
Vapour Pressure: 81.7 mmHg at 25°C 
The Cas Register Number of  1,2-Dimethylhydrazine is 540-73-8 .The chemical synonyms of  1,2-Dimethylhydrazine (CAS NO.540-73-8) are Hydrazine, 1,2-dimethyl-  and 1,1'-Dimethylhydrazine Dihydrochloride .The molecular structure of  1,2-Dimethylhydrazine (CAS NO.540-73-8) is.

1,2-Dimethylhydrazine Uses

 1,2-Dimethylhydrazine (CAS NO.540-73-8) is used in organic synthesis.

1,2-Dimethylhydrazine Toxicity Data With Reference

1.    

otr-hmn:fbr 230 µmol/L

    CALEDQ    Cancer Letters (Shannon, Ireland). 29 (1985),265.
2.    

dns-hmn:lng 100 µL/L

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD-A041-973 .
3.    

sce-mus-rec 20 mg/kg

    ENMUDM    Environmental Mutagenesis. 8 (Suppl 6)(1986),41.
4.    

hma-mus/esc 50 µmol/kg

    MUREAV    Mutation Research. 148 (1985),1.
5.    

dnd-ham:lng 2 mmol/L

    MUREAV    Mutation Research. 173 (1986),157.
6.    

sce-mus-ipr 270 µmol/kg

    TCMUD8    Teratogenesis, Carcinogenesis, and Mutagenesis. 9 (1989),219.
7.    

orl-rat LD50:100 mg/kg

    NATWAY    Naturwissenschaften. 54 (1967),285.
8.    

ihl-rat LCLo:280 ppm/4H

    AMIHAB    AMA Archives of Industrial Health. 12 (1955),609.
9.    

ipr-rat LD50:163 mg/kg

    MEPAAX    Medycyna Pracy. Industrial Medicine. 24 (1973),71.
10.    

scu-rat LD50:220 mg/kg

    XENOBH    Xenobiotica. 3 (1973),271.
11.  

1,2-Dimethylhydrazine Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 4 ,1974,p. 145.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

1,2-Dimethylhydrazine Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and intramuscular routes. Moderately toxic by inhalation. Human mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. A high-energy propellant for liquid-fueled rockets. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: ToxicT,DangerousN
Risk Statements: 45-23/24/25-51/53 
R45: May cause cancer. 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed. 
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-45-61 
S53: Avoid exposure - obtain special instructions before use. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2382
HazardClass: 6.1(a)
PackingGroup: I

1,2-Dimethylhydrazine Standards and Recommendations

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
DOT Classification:  3; Label: Flammable Liquid, Poison

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