- 31642-90-7Benzamide,3-amino-4-(4-morpholinyl)-
- 3164-29-2Butanedioic acid,2,3-dihydroxy- (2R,3R)-, ammonium salt (1:2)
- 3164-34-9Butanedioic acid,2,3-dihydroxy- (2R,3R)-, calcium salt (1:1)
- 31643-49-94-Nitrophthalonitrile
- 31645-34-82-Propenoic acid,9-anthracenylmethyl ester
- 31645-35-92-Propenoic acid,2-methyl-, 9-anthracenylmethyl ester
- 31645-39-3Phosphorodiamidic acid,N,N'-bis(2-chloroethyl)-
- 3164-60-1Phosphorous acid,bis(2-ethylhexyl) phenyl ester
- 316-46-15-Fluorouridine
- 3164-85-0Hexanoic acid,2-ethyl-, potassium salt (1:1)
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
| Name |
1-Emetine dihydrochloride |
EINECS | 206-259-8 |
| CAS No. | 316-42-7 | Density | g/cm3 |
| PSA | 52.19000 | LogP | 6.81410 |
| Solubility | > 10 mg/ml at 21 C | Melting Point |
240-250 °C (dec., dry matter)(lit.) |
| Formula | C29H40 N2 O4 . 2 Cl H | Boiling Point | 600.3 °C at 760 mmHg |
| Molecular Weight | 553.569 | Flash Point | 316.9 °C |
| Transport Information | UN 1544 6 | Appearance | white powder or crystals |
| Safety | A poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: diarrhea, distorted perceptions, dyspnea, hallucinations, hypermotility, nausea or vomiting. A human eye irritant. When heated to decomposition it emits very toxic fumes of Cl− and NOx. | Risk Codes | 28-36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 T+
|
| Synonyms |
2H-Benzo[a]quinolizine,3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[(1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl)methyl]-,dihydrochloride (6CI); 2H-Benzo[a]quinolizine,3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-,dihydrochloride, (2S,3R,11bS)- (9CI); Emetan, 6',7',10,11-tetramethoxy-,dihydrochloride; Emetine, dihydrochloride (8CI); (-)-Emetine dihydrochloride;Emetine hydrochloride; Hemometina; l-Emetine dihydrochloride |
1-Emetine dihydrochloride Chemical Properties
IUPAC Name: 2-[(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline dihydrochloride
The MF of 1-Emetine dihydrochloride (CAS NO.316-42-7) is C29H42Cl2N2O4.
.png)
The MW of 1-Emetine dihydrochloride (CAS NO.316-42-7) is 553.56.
Synonyms of 1-Emetine dihydrochloride (CAS NO.316-42-7): 2H-Benzo[a]quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-, (2S,3R,11bS)-, dihydrochloride ; Emetan, 6',7',10,11-tetramethoxy-, dihydrochloride
Product Categories: Miscellaneous Natural Products;Alkaloids;Biochemistry;Isoquinoline Alkaloids;Antibiotics;Antibiotics A to;Antibiotics A-FAntibiotic
Apperance: white powder or crystals
Stability: Stable. Combustible
Flash Point: 316.9 °C
Boiling Point: 600.3 °C
Melting Point: 240-250 °C
EINECS: 206-259-8
Storage temp: 2-8 °C
Merck: 3559
1-Emetine dihydrochloride Uses
1-Emetine dihydrochloride (CAS NO.316-42-7) is used as chemical reagent, organic intermediates, fine chemicals, pharmaceutical research and development.
1-Emetine dihydrochloride Toxicity Data With Reference
| 1. | eye-hmn 3250 µg | BJIMAG British Journal of Industrial Medicine. 4 (1947),111. | ||
| 2. | scu-wmn LDLo:2770 µg/kg/4D-I:BAH,GIT | AIMDAP Archives of Internal Medicine. 17 (1916),420. | ||
| 3. | scu-man LDLo:25 mg/kg/20D-I:GIT.PUL | AIMDAP Archives of Internal Medicine. 17 (1916),420. | ||
| 4. | orl-rat LD50:12 µg/kg | ANTCAO Antibiotics and Chemotherapy. 8 (1958),297. | ||
| 5. | ipr-rat LD50:17 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 94 (1948),431. | ||
| 6. | orl-mus LD50:15 µg/kg | ANTCAO Antibiotics and Chemotherapy. 8 (1958),297. | ||
| 7. | ipr-mus LD50:62 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 94 (1948),431. | ||
| 8. | scu-mus LD50:37 mg/kg | JPPMAB Journal of Pharmacy and Pharmacology. 16 (1964),65. | ||
| 9. | scu-mky LDLo:13,886 µg/kg | IMGAAY Indian Medical Gazette. 49 (1914),85. | ||
| 10. | orl-cat LDLo:15 mg/kg | AJTMAQ American Journal of Tropical Medicine. 10 (1930),249. | ||
| 1 |
1-Emetine dihydrochloride Consensus Reports
EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.
1-Emetine dihydrochloride Safety Profile
A poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: diarrhea, distorted perceptions, dyspnea, hallucinations, hypermotility, nausea or vomiting. A human eye irritant. When heated to decomposition it emits very toxic fumes of Cl− and NOx.Safety information of 1-Emetine dihydrochloride (CAS NO.316-42-7):
Hazard Codes 
T+
Risk Statements
28 Very Toxic if swallowed
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36/37 Wear suitable protective clothing and gloves
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR UN 1544 6.1/PG 1
WGK Germany 3
RTECS JY5250000
F 3-8-10
HazardClass 6.1(a)
PackingGroup I
1-Emetine dihydrochloride Specification
When heated to decomposition, It emits very toxic fumes of chlorides, hydrogen chloride and oxides of nitrogen. Turns yellow on exposure to light or heat [EPA, 1998].
What can I do for you?
Get Best Price
