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2,2'-Dimethyl[1,1'-biphenyl]-4,4'-diamine

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Name

2,2'-Dimethyl[1,1'-biphenyl]-4,4'-diamine

EINECS 201-551-1
CAS No. 84-67-3 Density 1.106 g/cm3
PSA 52.04000 LogP 4.29720
Solubility N/A Melting Point 105-106 °C
Formula C14H16N2 Boiling Point 344.4 °C at 760 mmHg
Molecular Weight 212.294 Flash Point 192.9 °C
Transport Information N/A Appearance N/A
Safety 24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 84-67-3 (M-TOLIDINE) Hazard Symbols N/A
Synonyms

NSC 1989;m-TBHG;m-Tolidine;Benzidine,2,2'-dimethyl- (7CI,8CI);2,2'-Dimethyl-4,4'-diaminobiphenyl;2,2'-Dimethylbenzidine;2,2'-Tolidine;4,4'-Diamino-2,2'-dimethylbiphenyl;

Article Data 20

2,2'-Dimethyl[1,1'-biphenyl]-4,4'-diamine Synthetic route

99-08-1

1-methyl-3-nitrobenzene

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
With 1,4-dihydroxy-9,10-anthracenedione; platinum on activated charcoal; hydrogen; sodium hydroxide In 5,5-dimethyl-1,3-cyclohexadiene; water at 65 - 75℃; under 6750.68 Torr; for 8h; Solvent; Reagent/catalyst; Pressure; Temperature; Autoclave;79.2%
With sodium hydroxide; ethanol; zinc man gibt weitere 150 g Zinkstaub hinzu und kocht dann mit Salzsaeure; das ausgeschiedene Tolidinhydrochlorid bringt man durch Wasser in Loesung und faellt es durch konz.Salzsaeure wieder aus;
(i) Zn, aq. NaOH, (ii) aq. HCl, Et2O; Multistep reaction;
Multi-step reaction with 3 steps
1: alcoholic potash
2: alcoholic ammonium sulfide
3: diluted alcohol; diluted sulfuric acid
View Scheme
Multi-step reaction with 2 steps
1: zinc; sodium hydroxide / water; ethanol / 4 h / Reflux; Inert atmosphere
2: hydrogenchloride / water / 5 h / Inert atmosphere; Reflux
View Scheme
59517-20-3

2,2'-dimethyl-4,4'-dinitro-biphenyl

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
With 3% Pd/C; hydrazine In ethanol at 100℃; for 12h;76%
With ethanol; nickel Hydrogenation;
With hydrogenchloride; zinc
588-04-5

3,3'-dimethylazobenzene

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
With hydrogenchloride; ethanol; tin(ll) chloride
With hydrogen sulfide; ammonia Durch Ansaeuern des Reaktionsproduktes mit Salzsaeure;
Multi-step reaction with 2 steps
1: alcoholic ammonium sulfide
2: diluted alcohol; diluted sulfuric acid
View Scheme
With hydrogenchloride; sulfur dioxide; potassium iodide
621-26-1

3,3'-dimethylhydrazobenzene

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
With ethanol; sulfuric acid
With hydrogenchloride In water for 5h; Inert atmosphere; Reflux;
621-26-1

3,3'-dimethylhydrazobenzene

acid

acid

84-67-3

2,2'-dimethylbenzidine

64-17-5

ethanol

588-04-5

3,3'-dimethylazobenzene

HCl-salt tin dichloride

HCl-salt tin dichloride

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
durch elektrochemischen Reduktion;
7647-01-0

hydrogenchloride

7782-99-2

sulphurous acid

588-04-5

3,3'-dimethylazobenzene

potassium iodide

potassium iodide

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
at 40 - 50℃;
5326-38-5

2-iodo-5-nitrotoluene

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: copper-powder / 280 °C
2: Raney nickel; ethanol / Hydrogenation
View Scheme
1221066-39-2

C40H32N2

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water at 20℃; for 2h;
7149-70-4

2-bromo-5-nitrotoluene

84-67-3

2,2'-dimethylbenzidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: copper / N,N-dimethyl-formamide / 12 h / 160 °C
2: hydrazine; 3% Pd/C / ethanol / 12 h / 100 °C
View Scheme

2,2'-Dimethyl[1,1'-biphenyl]-4,4'-diamine Specification

The IUPAC name of 2,2'-Dimethyl[1,1'-biphenyl]-4,4'-diamine is 4-(4-amino-2-methylphenyl)-3-methylaniline . With the CAS registry number 84-67-3, it is also named as 2,2'-Dimethyl-4,4'-biphenyldiamine ; 2,2'-Dimethylbenzidine ; 2,2'-Tolidine ; 4,4'-Diamino-2,2'-dimethylbiphenyl ; (1,1'-Biphenyl)-4,4'-diamine, 2,2'-dimethyl- (9CI) ; Benzidine, 2,2'-dimethyl- (8CI) . This product is the intermediates of Dyes and Pigments. It must be stored in the container and keep the container in the cool and dry place.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.48 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 2.39 ; (4)ACD/LogD (pH 7.4): 2.48 ; (5)ACD/BCF (pH 5.5): 36.45 ; (6)ACD/BCF (pH 7.4): 45.27 ; (7)ACD/KOC (pH 5.5): 428.86 ; (8)ACD/KOC (pH 7.4): 532.68 ; (9)#H bond acceptors: 2 ; (10)#H bond donors: 4 ; (11)#Freely Rotating Bonds: 3 ; (12)Index of Refraction: 1.638 ; (13)Molar Refractivity: 68.96 cm3 ; (14)Molar Volume: 191.8 cm3 ; (15)Polarizability: 27.34×10-24 cm3 ; (16)Surface Tension: 49 dyne/cm ; (17)Enthalpy of Vaporization: 58.83 kJ/mol ; (18)Vapour Pressure: 6.61E-05 mmHg at 25°C ; (19)Rotatable Bond Count: 1 ; (20)Exact Mass: 212.131349 ; (21)MonoIsotopic Mass: 212.131349 ; (22)Topological Polar Surface Area: 52 ; (23)Heavy Atom Count: 16.

People can use the following data to convert to the molecule structure. SMILES: c2(c(c1c(cc(N)cc1)C)ccc(N)c2)C; InChI: InChI=1/C14H16N2/c1-9-7-11(15)3-5-13(9)14-6-4-12(16)8-10(14)2/h3-8H,15-16H2,1-2H3. The 2,2'-Dimethyl[1,1'-biphenyl]-4,4'-diamine has many suppliers, such as Changzhou Sunlight Pharmaceutical Co., Ltd.. The price of this product changes with the market.

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