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2,3-Lutidine

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Name

2,3-Lutidine

EINECS 209-514-1
CAS No. 583-61-9 Density 0.93 g/cm3
PSA 12.89000 LogP 1.69840
Solubility 95 g/L (26 ºC) Melting Point -15 °C(lit.)
Formula C7H9N Boiling Point 160.7 °C at 760 mmHg
Molecular Weight 107.155 Flash Point 45.4 °C
Transport Information UN 1993 3/PG 3 Appearance clear colorless to slightly yellow liquid
Safety 16-26-39-36/37-36/37/39 Risk Codes 10-22-37/38-41-20/21/22-36/37/38
Molecular Structure Molecular Structure of 583-61-9 (2,3-Lutidine) Hazard Symbols HarmfulXn, FlammableF, IrritantXi
Synonyms

2,3-Lutidine(8CI);2,3-Dimethylpyridine;NSC 2157;

Article Data 32

2,3-Lutidine Synthetic route

87851-05-6

2-Methyl-3-acetoxymethylpyridin

583-61-9

2,3-Lutidine

Conditions
ConditionsYield
With hydrogen; Pd-BaSO4 In ethanol for 0.5h; Ambient temperature;99.2%

N-(3-methyl-2-methyl-2H-pyridin-1-yl)-N-methyl-benzamidine

583-61-9

2,3-Lutidine

Conditions
ConditionsYield
Stage #1: N-(3-methyl-2-methyl-2H-pyridin-1-yl)-N-methyl-benzamidine With manganese triacetate; acetic acid at 60℃; for 2h;
Stage #2: With water; acetic acid at 80℃;
81%
326893-28-1

5-chloro-5,6-dimethyl-2,3,4,5-tetrahydropyridine

583-61-9

2,3-Lutidine

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran Heating;80%
78-93-3

butanone

A

583-61-9

2,3-Lutidine

B

1462-84-6

2,3,6-trimethylpyridine

C

2233-29-6

2,3,4-lutidine

Conditions
ConditionsYield
With ammonia; chromium(III) oxide; aluminium at 350℃;A 30.7%
B 46.2%
C 23%
78-93-3

butanone

A

108-48-5

2,6-dimethylpyridine

B

583-61-9

2,3-Lutidine

C

1462-84-6

2,3,6-trimethylpyridine

D

2233-29-6

2,3,4-lutidine

Conditions
ConditionsYield
With ammonia; chromium(III) oxide; aluminium at 375℃;A 6.8%
B 24.6%
C 45.4%
D 25.7%
With ammonia; chromium(III) oxide; aluminium at 425℃;A 25.3%
B 34.5%
C 13.8%
D 13.8%
With ammonia; chromium(III) oxide; aluminium at 450℃;A 21.8%
B 22.4%
C 29.4%
D 11.7%
With ammonia; chromium(III) oxide; aluminium at 300 - 450℃; Product distribution;
108-99-6

3-Methylpyridine

A

110-86-1

pyridine

B

109-06-8

α-picoline

C

583-61-9

2,3-Lutidine

D

108-47-4

2,4-lutidine

E

589-93-5

2,5-dimethylpyridine

Conditions
ConditionsYield
With hydrogen; aluminum oxide; nickel at 330℃; under 750.06 Torr; Product distribution;A 0.3%
B 0.5%
C 5.3%
D 8%
E 30.9%
50-00-0

formaldehyd

75-07-0

acetaldehyde

67-64-1

acetone

A

583-61-9

2,3-Lutidine

B

536-78-7

3-ethylpyridine

C

2233-29-6

2,3,4-lutidine

D

108-99-6

3-Methylpyridine

Conditions
ConditionsYield
With diammonium phosphate In ethanol; water at 234℃; for 1h;A 25%
B 8%
C 13%
D 22%
109-06-8

α-picoline

A

110-86-1

pyridine

B

108-48-5

2,6-dimethylpyridine

C

583-61-9

2,3-Lutidine

D

589-93-5

2,5-dimethylpyridine

Conditions
ConditionsYield
With hydrogen; aluminum oxide; nickel at 330℃; under 750.06 Torr; Product distribution;A 14.9%
B 11.4%
C 3%
D 1.6%
412320-62-8

5,6-dimethyl-1,2,3,4-tetrahydro-pyridine

583-61-9

2,3-Lutidine

Conditions
ConditionsYield
With magnesium hydrosilicate; hydrogen; palladium at 280℃;
72093-13-1

6-chloro-2,3-dimethylpyridine

583-61-9

2,3-Lutidine

Conditions
ConditionsYield
With ethanol; palladium Hydrogenation;

2,3-Lutidine Chemical Properties

Molecule structure of 2,3-Lutidine (CAS NO.583-61-9):

IUPAC Name: 2,3-Dimethylpyridine 
Molecular Weight: 107.15306 g/mol
Molecular Formula: C7H9
Density: 0.93 g/cm3 
Melting Point: −15 °C(lit.)
Boiling Point: 160.7 °C at 760 mmHg 
Flash Point: 45.4 °C
Index of Refraction: 1.501
Molar Refractivity: 33.99 cm3
Molar Volume: 115.2 cm3
Surface Tension: 33.2 dyne/cm 
Enthalpy of Vaporization: 39.08 kJ/mol
Vapour Pressure: 3.07 mmHg at 25 °C 
Storage Temp.: flammables area
Water Solubility: 95 g/L (26 °C)
XLogP3-AA: 1.6
H-Bond Acceptor: 1
Exact Mass: 107.073499
MonoIsotopic Mass: 107.073499
Topological Polar Surface Area: 12.9
Heavy Atom Count: 8
Canonical SMILES: CC1=C(N=CC=C1)C
InChI: InChI=1S/C7H9N/c1-6-4-3-5-8-7(6)2/h3-5H,1-2H3
InChIKey: HPYNZHMRTTWQTB-UHFFFAOYSA-N
EINECS: 209-514-1
Product Categories: Pyridines derivates; Heterocyclic Compounds; Biochemistry; Reagents for Oligosaccharide Synthesis

2,3-Lutidine Safety Profile

Hazard Codes: HarmfulXn, FlammableF, IrritantXi
Risk Statements: 10-22-37/38-41-20/21/22-36/37/38 
R10:Flammable. 
R22:Harmful if swallowed. 
R37/38:Irritating to respiratory system and skin. 
R41:Risk of serious damage to the eyes. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 16-26-39-36/37-36/37/39 
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S39:Wear eye / face protection. 
S36/37:Wear suitable protective clothing and gloves. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
HazardClass: 6.1
PackingGroup: II

2,3-Lutidine Specification

 2,3-Lutidine (CAS NO.583-61-9) is also named as 2,3-Dimethylpyridine ; AI3-24280 ; NSC 2157 ; 2,3-Lutidine (8CI) ; Pyridine, 2,3-dimethyl- . 2,3-Lutidine (CAS NO.583-61-9) is clear colorless to slightly yellow liquid.

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