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Cas Database |
| Name |
2-METHYL-4-AMINO-5-ETHOXYMETHYL-PYRIMIDINE |
EINECS | N/A |
| CAS No. | 73-66-5 | Density | 1.113g/cm3 |
| PSA | 61.03000 | LogP | 1.48490 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C8H13 N3 O | Boiling Point | 276.4°C at 760 mmHg |
| Molecular Weight | 167.211 | Flash Point | 121°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | A poison by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Pyrimidine,4-amino-5-(ethoxymethyl)-2-methyl- (6CI,7CI,8CI);2-Methyl-4-amino-5-(ethoxymethyl)pyrimidine; 2-Methyl-5-(ethoxymethyl)-6-aminopyrimidine;4-Amino-2-methyl-5-(ethoxymethyl)pyrimidine;4-Amino-5-(ethoxymethyl)-2-methylpyrimidine; NSC 41790 |
Article Data | 15 |
2-METHYL-4-AMINO-5-ETHOXYMETHYL-PYRIMIDINE Synthetic route
- 749835-80-1
2-methyl-5-ethoxymethyl-6-chloropyrimidine
- 73-66-5
5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine
| Conditions | Yield |
|---|---|
| With ammonia In methanol at 140℃; for 4.5h; Autoclave; | 82% |
| With ethanol; ammonia at 140℃; |
- 109-95-5
ethyl nitrite
- 874-43-1, 1195-07-9, 25449-06-3
5-(aminomethyl)-2-methylpyrimidin-4-amine dihydrochloride
- 73-66-5
5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine
| Conditions | Yield |
|---|---|
| With ethanol at 90 - 100℃; |
- 3699-10-3
2-ethoxymethyl-3c-methoxy-acrylonitrile
- 143-37-3
acetamidine
- 73-66-5
5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine
| Conditions | Yield |
|---|---|
| With ethanol |
- 3699-12-5
3c-ethoxy-2-ethoxymethyl-acrylonitrile
- 143-37-3
acetamidine
- 73-66-5
5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine
| Conditions | Yield |
|---|---|
| With ethanol |
| Conditions | Yield |
|---|---|
| With ethanol; benzene |
| Conditions | Yield |
|---|---|
| Erwaermen des Reaktionsprodukts mit 10prozentig.KOH; | |
| Erwaermen des Reaktionsprodukts mit 10prozentig.KOH;Geschwindigkeit; |
- 99764-73-5
3-t-butoxypropanenitrile
- 124-42-5
acetamidine hydrochloride
- 109-94-4
formic acid ethyl ester
A
- 73-66-5
5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine
B
- 127556-60-9
2-methyl-4-amino-5-tert-butoxymethylpyrimidine
| Conditions | Yield |
|---|---|
| Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: ethyl formate; benzene / beim Erwaermen des Reaktionsgemisches mit Dimethylsulfat 2: ethanol View Scheme | |
| Multi-step reaction with 2 steps 1: ethyl formate; benzene / beim Erwaermen des Reaktionsgemisches mit Diaethylsulfat 2: ethanol View Scheme |
- 5423-97-2
5-ethoxymethyl-2-methyl-3H-pyrimidin-4-one
- 73-66-5
5-ethoxymethyl-2-methyl-pyrimidin-4-ylamine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: POCl3 2: ethanol; NH3 / 140 °C View Scheme |
2-METHYL-4-AMINO-5-ETHOXYMETHYL-PYRIMIDINE Toxicity Data With Reference
| 1. | orl-rat LD50:1450 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,81. | ||
| 2. | orl-mus LD50:239 mg/kg | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,81. |
2-METHYL-4-AMINO-5-ETHOXYMETHYL-PYRIMIDINE Safety Profile
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