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CAS No. 610-67-3 Density 1.19
PSA 55.05000 LogP 2.51670
Solubility N/A Melting Point 1.1°C
Formula C8H9 N O3 Boiling Point 275 °C
Molecular Weight 167.164 Flash Point 4 °C
Transport Information N/A Appearance N/A
Safety Mutation data reported. When heated to decomposition it emits toxic vapors of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 610-67-3 (2-NITROPHENETOLE) Hazard Symbols Xi

Phenetole,o-nitro- (7CI,8CI); 1-Ethoxy-2-nitrobenzene; 2-Ethoxynitrobenzene;2-Nitrophenetole; Ethyl o-nitrophenyl ether; NSC 5404; o-Nitrobenzene ethylether; o-Nitrophenetole

Article Data 39

2-Nitrophenetole Chemical Properties

Chemistry informtion about O-Nitrophenetole (CAS NO.610-67-3) is:
IUPAC Name: 1-Ethoxy-2-Nitrobenzene
Synonyms: 1-Ethoxy-2-Nitro-Benzen ; 2-Ethoxynitrobenzene ; 2-Nitrophenylethylether ; Benzene, 1-Ethoxy-2-Nitro- ; Benzene,1-Ethoxy-2-Nitro- ; Ethyl O-Nitrophenyl Ether ; Ethylo-Nitrophenylether ; O-Nitro-Phenetol
Product Categories: Intermediates of Dyes and Pigments ; Phenetole
MW: 167.16
EINECS: 210-232-6 
Density: 1.178 g/cm3
Flash Point: 127.3 °C
Boiling Point: 269.6 °C at 760 mmHg
Vapour Pressure: 0.0119 mmHg at 25°C 
Enthalpy of Vaporization: 48.73 kJ/mol
Following is the molecular structure of O-Nitrophenetole (CAS NO.610-67-3) is:

2-Nitrophenetole Production

Preparation Products is O-Phenetidine .

2-Nitrophenetole Toxicity Data With Reference


mmo-sat 1 µmol/plate

    MUREAV    Mutation Research. 58 (1978),11.

dnr-bcs 500 nL/disc

    MUREAV    Mutation Research. 170 (1986),11.

2-Nitrophenetole Consensus Reports

Reported in EPA TSCA Inventory.

2-Nitrophenetole Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx
Hazard Codes:
RTECS: SI7942000
Hazard Note: Irritant

2-Nitrophenetole Analytical Methods

A process for the preparation of O-Nitrophenetole (CAS NO.610-67-3) by allowing about 1.05 to about 1.4 mole of ethanol to act on 1 mole of o-nitrochlorobenzene in the presence of a phase-transfer catalyst in approximately 40 to approximately 70 percent by weight alkali metal hydroxide solution at temperatures from about 50°C to about 80°C. in such a way that the ethanol concentration in the reaction mixture does not exceed 1.5 percent by weight throughout the course of the reaction.

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