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2-Phenyl-3-butyn-2-ol

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Name

2-Phenyl-3-butyn-2-ol

EINECS 204-855-2
CAS No. 127-66-2 Density 1.064g/cm3
PSA N/A LogP N/A
Solubility N/A Melting Point 48-52 °C

Formula C10H10 O Boiling Point 102-103 °C12 mm Hg(lit.)
Molecular Weight 146.189 Flash Point 96 ºC
Transport Information N/A Appearance N/A
Safety Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating vapors. Risk Codes R22   
Molecular Structure Molecular Structure of 127-66-2 (2-PHENYL-3-BUTYN-2-OL) Hazard Symbols
Synonyms

3-Butyn-2-ol,2-phenyl- (6CI,7CI,8CI); Benzyl alcohol, a-ethynyl-a-methyl- (4CI); 2-Hydroxy-2-phenyl-3-butyne; 2-Phenyl-2-hydroxy-3-butyne;2-Phenyl-3-butyn-2-ol; 3-Phenyl-1-butyn-3-ol; 3-Phenylbutyn-3-ol;Ethynylmethylphenylcarbinol; Methylphenylethynylcarbinol; NSC 4329; a-Ethynyl-a-methylbenzenemethanol

Article Data 72

2-Phenyl-3-butyn-2-ol Chemical Properties

Molecular Formula: C10H10O
Molar mass: 146.1858 g/mol
EINECS: 204-855-2
Density: 1.064 g/cm3
Flash Point: 96.1 °C
Index of Refraction: 1.553
Boiling Point: 217.5 °C at 760 mmHg
Vapour Pressure: 0.0771 mmHg at 25°C
Melting point: 48-52 °C
Storage temp: 2-8°C
Appearance: White semi-transparent crystals
Product categories: Alkynes;Terminal;Organic Building Blocks
Structure of 2-Phenyl-3-butyn-2-ol (CAS NO.127-66-2):
             
XLogP3-AA: 1.5
H-Bond Donor: 1
H-Bond Acceptor: 1
IUPAC Name: 2-Phenylbut-3-yn-2-ol
Canonical SMILES: CC(C#C)(C1=CC=CC=C1)O
InChI: InChI=1S/C10H10O/c1-3-10(2,11)9-7-5-4-6-8-9/h1,4-8,11H,2H3 
InChIKey: KSLSOBUAIFEGLT-UHFFFAOYSA-N

2-Phenyl-3-butyn-2-ol Toxicity Data With Reference

1.    

orl-mus LD50:620 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 4 (1954),477.

Carcinogenicity of 2-Phenyl-3-butyn-2-ol (CAS NO.127-66-2) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. You can see actual entry in RTECS for complete information.

2-Phenyl-3-butyn-2-ol Consensus Reports

Reported in EPA TSCA Inventory.

2-Phenyl-3-butyn-2-ol Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating vapors.
 

Hazard Codes: HarmfulXn
Risk Statements: 22
R22:Harmful if swallowed.
Safety Statements: 22-24/25
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes.
 

2-Phenyl-3-butyn-2-ol Specification

 2-Phenyl-3-butyn-2-ol ,its cas register number is 127-66-2. It also can be called 3-Hydroxy-3-phenyl-1-butyne ; 2-Phenylbut-3-yn-2-ol ; 3-Butyn-2-ol, 2-phenyl- ; 3-Phenyl-butin-1-ol-(3) and Methylphenylethynylcarbinol . 2-Phenyl-3-butyn-2-ol (CAS NO.127-66-2) is hazardous,so the first aid measures and others should be known. Such as: When on the skin: first,should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly,Get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While ,it's Inhaled: Remove from exposure and move to fresh air immediately.Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.
In addition, 2-Phenyl-3-butyn-2-ol (CAS NO.127-66-2) can be stable under normal temperature and pressure conditions.It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: carbon dioxide, carbon monoxide.

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