Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
3,4,5-Trimethoxyphenylacetonitrile |
EINECS | 236-388-5 |
CAS No. | 13338-63-1 | Density | 1.104 g/cm3 |
PSA | 51.48000 | LogP | 1.77848 |
Solubility | Insoluble in water | Melting Point |
76-79 ºC |
Formula | C11H13 N O3 | Boiling Point | 327.9 °C at 760 mmHg |
Molecular Weight | 207.229 | Flash Point | 132.8 °C |
Transport Information | N/A | Appearance | white crystalline powder |
Safety | S24/25 | Risk Codes | R20/21/22 |
Molecular Structure | Hazard Symbols | ||
Synonyms |
Acetonitrile,(3,4,5-trimethoxyphenyl)- (6CI,7CI,8CI); (3,4,5-Trimethoxyphenyl)acetonitrile;2-(3,4,5-Trimethoxyphenyl)acetonitrile; 3,4,5-Trimethoxybenzeneacetonitrile;3,4,5-Trimethoxybenzyl cyanide; 3,4,5-Trimethoxybenzylnitrile; NSC 97556 |
Article Data | 36 |
Oxime of 3,4,5-trimethoxyphenylpyruvic acid
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
With 1,1'-oxalyldiimidazole In benzene 1.) r.t., 15 min, 2.) 68-70 deg C, 1 h; | 88% |
With acetic anhydride | |
With acetic anhydride for 0.0833333h; Heating; |
3,4,5-trimethoxyphenyl acetic acid
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
With sodium azide; TEA; triethylphosphine; (bis-(2-methoxyethyl)amino)sulfur trufluoride In dichloromethane; dimethyl sulfoxide at 0℃; for 50h; | 88% |
sodium cyanide
5-(chloromethyl)-1,2,3-trimethoxybenzene
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 20℃; for 36h; | 85% |
In acetonitrile Reflux; | |
In acetonitrile for 4h; Reflux; | |
In dimethyl sulfoxide |
2,3,4-trimethoxybromobenzene
acetonitrile
A
2-(3,4,5-trimethoxyphenyl)acetonitrile
B
Bis-(3,4,5-trimethoxy-phenyl)-acetonitrile
Conditions | Yield |
---|---|
With ethoxyethoxyethanol; sodium amide In 1,2-dimethoxyethane 1.) 45 deg C, 2 h, 2.) -10 deg C, 2 h, 3.) -30 deg C, 4.5 h; | A 83% B 11% |
3,4,5-trimethoxybenzyl bromide
sodium cyanide
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
In dimethyl sulfoxide Ambient temperature; | 75% |
3,4,5-trimethoxybenzoyl cyanide
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
With sodium sulfate; ethanethiol; zinc(II) chloride weiteres Reagens: Benzol; Erwaermen des Reaktionsprodukts mit Raney-Nickel in wss. Methanol; |
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
With acetic anhydride |
Oxime of 3,4,5-trimethoxyphenylpyruvic acid
acetic anhydride
2-(3,4,5-trimethoxyphenyl)acetonitrile
potassium cyanide
3,4,5-trimethoxy-benzaldehyde
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
With water; chloroformic acid ethyl ester; magnesium sulfate Hydrieren des Reaktionsprodukts an Palladium in Benzol; |
2,3,4-trimethoxybromobenzene
acetonitrile
2-(3,4,5-trimethoxyphenyl)acetonitrile
Conditions | Yield |
---|---|
With sodium amide 1.) liquid ammonia, 5 min, 2.) liquid ammonia, 15 min; Yield given. Multistep reaction; |