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3-Fluorotyrosin

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Name

3-Fluorotyrosin

EINECS 206-964-0
CAS No. 139-26-4 Density 1.421 g/cm3
PSA 83.55000 LogP 1.18600
Solubility N/A Melting Point 280 °C (dec.)(lit.)
Formula C9H10 F N O3 Boiling Point 362.4 °C at 760 mmHg
Molecular Weight 199.182 Flash Point 172.9 °C
Transport Information N/A Appearance N/A
Safety Human poison by ingestion. Experimental poison by ingestion, skin contact, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of F and NOx. See also FLUORIDES. Risk Codes 20/21/22
Molecular Structure Molecular Structure of 139-26-4 (3-FLUORO-DL-TYROSINE) Hazard Symbols HarmfulXn
Synonyms

DL-Tyrosine,3-fluoro-; Tyrosine, 3-fluoro-, DL- (8CI); 3-Fluoro-DL-tyrosine;3-Fluorotyrosine; Ba 2745; DL-3-Fluorotyrosin; DL-3-Fluorotyrosine;DL-m-Fluorotyrosine; Fluorthyrin; NSC 83231; Pardinon; m-Fluoro-DL-tyrosine

Article Data 1

3-Fluorotyrosin Chemical Properties

Chemistry informtion about 3-Fluorotyrosin (CAS NO.139-26-4) is:
IUPAC Name: 2-Amino-3-(3-Fluoro-4-Hydroxyphenyl)Propanoic Acid
Synonyms: Pardinon ; M-Fluoro-Dl-Tyrosine ; 3-Fluorotyrosin ; 3-Fluoro-Tyrosin ; 3-Fluortyrosin ; M-Fluorotyrosine ; Dl-3-Fluorotyrosine ; Dl-M-Fluorotyrosine
MF: C9H10FNO3
MW: 199.18
EINECS: 206-964-0 
Density: 1.421 g/cm3 
Melting Point: 280 °C (dec.)(lit.)
Flash Point: 172.9 °C
Boiling Point: 362.4 °C at 760 mmHg
Vapour Pressure: 6.94E-06 mmHg at 25°C 
Enthalpy of Vaporization: 64.18 kJ/mol
Storage temp.: 2-8°C
Following is the molecular structure of 3-Fluorotyrosin (CAS NO.139-26-4) is:

3-Fluorotyrosin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 8mg/kg (8mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
man LDLo oral 143mg/kg (143mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
mouse LDLo oral 14mg/kg (14mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
mouse LDLo skin 18mg/kg (18mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
mouse LDLo subcutaneous 11mg/kg (11mg/kg) behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
rat LDLo subcutaneous 12mg/kg (12mg/kg) behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold behavioral: irritability Journal of Pharmacology and Experimental Therapeutics. Vol. 73, Pg. 176, 1941.

3-Fluorotyrosin Safety Profile

Human poison by ingestion. Experimental poison by ingestion, skin contact, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of F and NOx. See also FLUORIDES
Hazard Codes:
HarmfulXn
Risk Statements:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements:
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: YP2660000

3-Fluorotyrosin Specification

First Aid Measures:
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. 
Handling and Storage:
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Keep container closed when not in use. Hormones and antibiotics room.

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