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3-Glycidoxypropyltrimethoxysilane

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Name

3-Glycidoxypropyltrimethoxysilane

EINECS 219-784-2
CAS No. 2530-83-8 Density 1.047 g/cm3
PSA 49.45000 LogP 0.67000
Solubility Miscible with alcohols, ketones and aliphatic or aromatic hydrocarbons. Immiscible with water. Melting Point -50 °C
Formula C9H20O5Si Boiling Point 299.4 °C at 760 mmHg
Molecular Weight 236.34 Flash Point 81.9 °C
Transport Information N/A Appearance Colorless transparent liquid
Safety 28A-26 Risk Codes 36/38-21
Molecular Structure Molecular Structure of 2530-83-8 (3-Glycidoxypropyltrimethoxysilane) Hazard Symbols HarmfulXn
Synonyms

((3-(Trimethoxysilyl)propoxy)methyl)oxirane;(3-(Glycidyloxy)propyl)trimethoxysilane;(3-Glycidoxypropyl)trimethoxysilane;1-(Glycidyloxy)-3-(trimethoxysilyl)propane;3-(2,3-Epoxypropoxy)propyltrimethoxysilane;Glycidyl 3-(trimethoxysilyl)propyl ether;Glycidyloxypropyltrimethoxysilane;

Article Data 10

3-Glycidoxypropyltrimethoxysilane Synthetic route

106-92-3

Allyl glycidyl ether

2487-90-3

trimethoxysilane

2530-83-8

3-glycidoxypropyltrimethoxysilane

Conditions
ConditionsYield
Stage #1: trimethoxysilane; C13H28N2OPtSi2 In xylene for 0.0833333h; Inert atmosphere; Reflux;
Stage #2: Allyl glycidyl ether In xylene for 2h; Product distribution / selectivity; Reflux;
82%
80%
With 2C4H9O(1-)*Ni(2+)*(x)KCl In tetrahydrofuran at 20℃; for 12h; Glovebox; Inert atmosphere;61%
106-92-3

Allyl glycidyl ether

2487-90-3

trimethoxysilane

A

2530-83-8

3-glycidoxypropyltrimethoxysilane

B

(Z)-1-propenyl glycidyl ether

Conditions
ConditionsYield
With acetic acid; platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 160℃; Product distribution / selectivity; tube reactor;
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; 2-Ethylhexanoic acid at 100℃; for 2h; Catalytic behavior; Reagent/catalyst; Temperature;
106-92-3

Allyl glycidyl ether

2487-90-3

trimethoxysilane

A

2530-83-8

3-glycidoxypropyltrimethoxysilane

B

(Z)-1-propenyl glycidyl ether

C

(E)-1-propenyl glycidyl ether

Conditions
ConditionsYield
platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 160℃; Product distribution / selectivity; tube reactor;
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex at 160℃; Temperature;

phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

2530-83-8

3-glycidoxypropyltrimethoxysilane

(2,4,6-trimethylbenzoyl)phenylphosphinic acid 2-hydroxy-[3-(3-trimethoxysilyl)propyloxy] propyl ester

Conditions
ConditionsYield
In n-heptane at 20℃; for 12h; Inert atmosphere;100%

phenyl(2,4,6-trimethylbenzoyl)phosphinic acid

30674-80-7

2-Isocyanatoethyl methacrylate

2530-83-8

3-glycidoxypropyltrimethoxysilane

C32H46NO11PSi

Conditions
ConditionsYield
With triethylamine In n-heptane at 20℃; Inert atmosphere;100%
2530-83-8

3-glycidoxypropyltrimethoxysilane

2349-67-9

2-Amino-5-mercapto-1,3,4-thiadiazole

C11H23N3O5S2Si

Conditions
ConditionsYield
Stage #1: 2-Amino-5-mercapto-1,3,4-thiadiazole In methanol
Stage #2: 3-glycidoxypropyltrimethoxysilane In methanol at 65℃; for 18h;
100%
In methanol at 65℃; for 18h;
2530-83-8

3-glycidoxypropyltrimethoxysilane

16691-43-3

5-amino-3-mercapto-4H-[1,2,4]triazole

C11H24N4O5SSi

Conditions
ConditionsYield
Stage #1: 5-amino-3-mercapto-4H-[1,2,4]triazole In methanol
Stage #2: 3-glycidoxypropyltrimethoxysilane In methanol at 65℃; for 18h; Solvent; Temperature;
100%
In methanol at 65℃; for 18h; Solvent;
5036-48-6

3-(1H-imidazol-1-yl)propan-1-amine

2530-83-8

3-glycidoxypropyltrimethoxysilane

1204776-56-6

C15H31N3O5Si

Conditions
ConditionsYield
In tetrahydrofuran at 95℃; for 6h; Inert atmosphere;98%
2530-83-8

3-glycidoxypropyltrimethoxysilane

C104H203N9O35Si8

C110H211N9O37Si9

Conditions
ConditionsYield
With titanium(IV) isopropylate In methanol; toluene Heating;97%
1254067-29-2

C14H18O5S

2530-83-8

3-glycidoxypropyltrimethoxysilane

1254067-30-5

C23H38O10SSi

Conditions
ConditionsYield
With triethylamine In dichloromethane at 40℃; Inert atmosphere;97%

3-Glycidoxypropyltrimethoxysilane Specification

The 3-Glycidoxypropyltrimethoxysilane, with the CAS registry number 2530-83-8, is also known as Trimethoxy[3-(2-oxiranylmethoxy)propyl]silane.It belongs to the product organic raw material. Its EINECS number is 219-784-2. This chemical's molecular formula is C9H20O5Si and molecular weight is 236.34. What's more,Its systematic name is gamma-Glycidoxypropyltrimethoxysilane.3-Glycidoxypropyltrimethoxysilane may cause damage to health. It is harmful in contact with skin and irritating to eyes and skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Physical properties about 3-Glycidoxypropyltrimethoxysilane are:
(1)ACD/LogP: 1.434; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.43; (4)ACD/LogD (pH 7.4): 1.43; (5)ACD/BCF (pH 5.5): 7.25; (6)ACD/BCF (pH 7.4): 7.25; (7)ACD/KOC (pH 5.5): 143.65; (8)ACD/KOC (pH 7.4): 143.65; (9)#H bond acceptors: 5; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 9; (12)Index of Refraction: 1.436; (13)Molar Refractivity: 59.018 cm3; (14)Molar Volume: 225.575 cm3; (15)Surface Tension: 29.4689998626709 dyne/cm; (16)Density: 1.048 g/cm3; (17)Flash Point: 81.947 °C; (18)Enthalpy of Vaporization: 51.777 kJ/mol; (19)Boiling Point: 299.352 °C at 760 mmHg; (20)Vapour Pressure: 0.0020000000949949 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES:O(CCC[Si](OC)(OC)OC)CC1OC1;
(2)Std. InChI:InChI=1S/C9H20O5Si/c1-10-15(11-2,12-3)6-4-5-13-7-9-8-14-9/h9H,4-8H2,1-3H3;
(3)Std. InChIKey:BPSIOYPQMFLKFR-UHFFFAOYSA-N;

The toxicity data of 3-Glycidoxypropyltrimethoxysilane as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LD50 skin 3970uL/kg (3.97mL/kg)   American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat LCLo inhalation 5300mg/m3/4H (5300mg/m3)   Office of Toxic Substances Report. Vol. OTS215156,
rat LCLo inhalation 5300mg/m3/4H (5300mg/m3) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE Office of Toxic Substances Report. Vol. OTS215156,
rat LD50 oral 22600uL/kg (22.6mL/kg)   Union Carbide Data Sheet. Vol. 2/11/1964,

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