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3-Indolyl acetate

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Name

3-Indolyl acetate

EINECS 210-154-2
CAS No. 608-08-2 Density 1.255 g/cm3
PSA 42.09000 LogP 2.09320
Solubility Soluble in ethanol, water, chloroform, dichloromethane and methanol. Melting Point 128-130 °C(lit.)
Formula C10H9NO2 Boiling Point 339.1 °C at 760 mmHg
Molecular Weight 175.187 Flash Point 158.9 °C
Transport Information N/A Appearance Dark blue solid
Safety 26-36 Risk Codes 22-36/37/38
Molecular Structure Molecular Structure of 608-08-2 (INDOXYL ACETATE) Hazard Symbols HarmfulXn
Synonyms

1H-Indol-3-ol,acetate (ester) (9CI);Indol-3-ol, acetate (7CI);Indol-3-ol, acetate (ester)(8CI);Indoxyl acetate (6CI);3-Acetoxyindole;3-Indolyl acetate;3-Indoxylacetate;NSC 13964;

Article Data 16

3-Indolyl acetate Synthetic route

120-72-9

indole

3240-34-4

[bis(acetoxy)iodo]benzene

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
With potassium hydroxide In acetonitrile at 35℃; for 1.5h;76%
With potassium hydroxide In toluene; acetonitrile at 20℃; for 1.5h; Green chemistry;

5-acetoxy-3-methoxycarbonyl-5H-1,2-benzodiazepine

A

608-08-2

3-indoxyl acetate

B

623-49-4

ethyl cyanoformate

Conditions
ConditionsYield
In dichloromethane for 0.133333h; Irradiation;A 74%
B n/a
120-72-9

indole

2570-63-0

thallium(III) acetate

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
With acetic acid at 30℃; for 2h;43%
26340-47-6

3-Iodo-1H-indole

563-63-3

silver(I) acetate

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
With acetic acid at 90℃; for 1h;41%
With acetic acid
100063-39-6

2-Acetyl-1H-indol-3-yl-acetat

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
With sodium hydroxide; water unter Stickstoff und Behandeln des Reaktionsprodukts mit Acetanhydrid bei 0grad;
612-42-0

phenylglycine-o-carboxylic acid

A

608-08-2

3-indoxyl acetate

B

1-acetyl-3-hydroxy-indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide at 260℃; Behandeln des mit CO2 und Essigsaeure teilweise neutralisierten Reaktionsgemisches mit Acetanhydrid;
480-93-3

indoxyl

108-24-7

acetic anhydride

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
With sulfuric acid; water
With alkali
With alkali
140843-81-8

1-Nitrosoindol-3-yl acetate

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
In 1,4-dioxane; water at 25℃; Equilibrium constant;
67790-18-5

3-methoxycarbonyl-5H-1,2-benzodiazepine

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 68 percent / CH2Cl2 / 0 - 20 °C
2: 74 percent / CH2Cl2 / 0.13 h / Irradiation
View Scheme
6245-93-8

3-hydroxy-1H-indole-2-carboxylic acid

608-08-2

3-indoxyl acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water / 70 - 80 °C
2: alkali
View Scheme
Multi-step reaction with 2 steps
2: alkali
View Scheme

3-Indolyl acetate Chemical Properties

Product Name: Indoxyl acetate  (608-08-2)


Molecular Formula: C10H9NO2
Molecular Weight: 175.18g/mol
Mol File: 608-08-2.mol
Einecs: 210-154-2
Appearance: Dark Blue Solid
Melting Point: 128-130 °C(lit.)
storage Temperature: 2-8°C
Product Categories: Indoles and derivatives ; Indole Derivatives ; Simple Indoles ; Indoles ; Intermediates .
Synonyms of Ethyl Indoxyl acetate  (608-08-2) : 3-acetoxyindole ; 3-indolyl acetate ; 3-indoxyl-3-acetate ; 3-indoxyl acetate ; acetic acid 3-indolyl ester ; 1h-indol-3-yl acetate ; indol-3-yl acetate ; indoxyl acetate ; 1h-indol-3-ol 3-acetate ; 1h-indol-3-ol acetate (ester) ; 3-acetoxyindole ; acetic acid ; 3-indolyl ester ; indol-3-ol acetate (ester) (8CI) .

3-Indolyl acetate Uses

 Indoxyl acetate  (608-08-2)  is mainly used as a plant growth-stimulating hormone and reagents.

3-Indolyl acetate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 600mg/kg (600mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 55, Pg. 1514, 1959.

3-Indolyl acetate Consensus Reports

Reported in EPA TSCA Inventory.

3-Indolyl acetate Safety Profile

Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx.
Safety Information of Ethyl Indoxyl acetate  (608-08-2):
Hazard Codes:  Xn
Risk Statements: 22-36/37/38
22:  Harmful if swallowed
36:  Irritating to the eyes
37:  Irritating to the respiratory system
38:  Irritating to the skin
Safety Statements: 26-36
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing

 

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