Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

3-METHYL-2-PYRAZOLIN-5-ONE

Related Products

Hot Products

Name

3-METHYL-2-PYRAZOLIN-5-ONE

EINECS 203-565-3
CAS No. 108-26-9 Density 1.33 g/cm3
PSA 41.46000 LogP -0.35340
Solubility Ethanol: slightly soluble Melting Point 220-224 ºC
Formula C4H6 N2 O Boiling Point 309.7oC at 760 mmHg
Molecular Weight 98.1044 Flash Point 141.1oC
Transport Information N/A Appearance pale white crystal powder
Safety Moderately toxic by unspecified route. When heated to decomposition it emits toxic vapors of NOx. Risk Codes 36/37/38
Molecular Structure Molecular Structure of 108-26-9 (3-Methyl-2-pyrazolin-5-one) Hazard Symbols N/A
Synonyms

2-Pyrazolin-5-one,3-methyl- (6CI,7CI,8CI); 2,4-Dihydro-5-methyl-3H-pyrazol-3-one;3-Methyl-1H-4,5-dihydropyrazol-5-one; 3-Methyl-2-pyrazolin-5-one;3-Methyl-5-oxo-2-pyrazoline; 3-Methyl-D2-pyrazol-5-one

Article Data 114

3-METHYL-2-PYRAZOLIN-5-ONE Synthetic route

141-97-9

ethyl acetoacetate

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
With hydrazine In tetrahydrofuran; ethanol at 0 - 60℃; for 26h; Inert atmosphere;100%
With hydrazine hydrate at 20℃; for 0.0333333h; Knorr Pyrazole Synthesis;100%
With hydrazine for 0.00833333h;94%

hydrazine hydrate

141-97-9

ethyl acetoacetate

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
With barium(II) hydroxide In water at 26℃; for 0.75h; Green chemistry;100%
105-45-3

acetoacetic acid methyl ester

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
With hydrazine hydrate In methanol at 50℃; for 3h; Temperature; Inert atmosphere;97.3%
With hydrazine In ethanol
27991-08-8

N-acetoacetylphenylhydroxyloamine

A

4329-75-3

N,N'-bis(isonicotinoyl)hydrazine

B

100-65-2

N-Phenylhydroxylamine

C

108-26-9

3-methyl-2-pyrazoline-5-one

D

495-48-7

azoxybenzene

Conditions
ConditionsYield
With isoniazid; triethylamine In chloroform for 24h; Heating; Further byproducts given;A 39.5%
B 32.7%
C 90%
D 22%
27991-08-8

N-acetoacetylphenylhydroxyloamine

54-85-3

isoniazid

A

4329-75-3

N,N'-bis(isonicotinoyl)hydrazine

B

100-65-2

N-Phenylhydroxylamine

C

143997-57-3

N-hydroxy-N-phenylisonicotinamide

D

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
triethylamine In chloroform for 24h; Heating; Further byproducts given;A 39.5%
B 32.7%
C 23%
D 90%
54-85-3

isoniazid

A

4329-75-3

N,N'-bis(isonicotinoyl)hydrazine

B

100-65-2

N-Phenylhydroxylamine

C

143997-57-3

N-hydroxy-N-phenylisonicotinamide

D

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
With N,O-diacetylphenylhydroxylamine; triethylamine In chloroform for 24h; Heating; Further byproducts given;A 39.5%
B 32.7%
C 23%
D 90%
141-97-9

ethyl acetoacetate

N2H4*H2O

N2H4*H2O

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
In ethanol Condensation; Cyclization;87%
116206-94-1

ethyl 2-acetyl-4,4,5,5,6,6,7,7,7-nonafluoro-3-oxoheptanoate

100-63-0

phenylhydrazine

A

77146-67-9

2,2,3,3,4,4,5,5,5-Nonafluoro-pentanoic acid N'-phenyl-hydrazide

B

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
In diethyl ether at -30 - -25℃; for 1h;A 84%
B n/a
115479-07-7

2-Acetyl-4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoro-3-oxo-nonanoic acid ethyl ester

100-63-0

phenylhydrazine

A

77146-68-0

2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid N'-phenyl-hydrazide

B

108-26-9

3-methyl-2-pyrazoline-5-one

Conditions
ConditionsYield
In diethyl ether at -30 - -25℃; for 1h;A 79%
B n/a
141-97-9

ethyl acetoacetate

269727-55-1

N-d-pseudoephedrinylacetic acid hydrazide

A

108-26-9

3-methyl-2-pyrazoline-5-one

B

206256-43-1

(5S,6S)-4,5-dimethyl-6-phenyl-2-morpholone

Conditions
ConditionsYield
In isopropyl alcohol for 10h; Condensation; cyclization; elimination; Heating;A n/a
B 68%

3-METHYL-2-PYRAZOLIN-5-ONE Chemical Properties

The Molecular formula of 3-METHYL-2-PYRAZOLIN-5-ONE(108-26-9): C4H6N2O
The Molecular Weight of 3-METHYL-2-PYRAZOLIN-5-ONE(108-26-9): 98.1
The Molecular Weight of 3-METHYL-2-PYRAZOLIN-5-ONE(108-26-9): 
EINECS: 203-565-3
Melting point: 220-224 °C 
Index of Refraction: 1.599 
Molar Refractivity: 25.2 cm
Molar Volume: 73.7 cm
Polarizability: 9.99 10-24 cm
Surface Tension: 45.6 dyne/cm 
Density: 1.33 g/cm
Appearance: Yellowish powder
Synonyms: TIMTEC-BB SBB004372;3-Methyl-pyrazolon-(5);52-Pyrazolin-5-one, 3-methyl-;3-METHYL-4,5-DIHYDRO-1H-PYRAZOL-5-ONE;3-METHYL-5-PYRAZOLONE;3-methyl-2-pyrazolin-5-on;-Methyl-2,4-dihydro-3H-pyrazol-3-one;AURORA KA-6219;

3-METHYL-2-PYRAZOLIN-5-ONE Uses

3-METHYL-2-PYRAZOLIN-5-ONE(108-26-9) is used as intermediate for the manufacture of dyestuffs as well as for agrochemicals.

3-METHYL-2-PYRAZOLIN-5-ONE Toxicity Data With Reference

1.   

unr-rat LDLo:600 mg/kg

   BCPCA6    Biochemical Pharmacology. 14 (1965),1325.

3-METHYL-2-PYRAZOLIN-5-ONE Consensus Reports

Reported in EPA TSCA Inventory.

3-METHYL-2-PYRAZOLIN-5-ONE Safety Profile

Moderately toxic by unspecified route. When heated to decomposition it emits toxic vapors of NOx.
The Risk Statements information of 3-METHYL-2-PYRAZOLIN-5-ONE(108-26-9):
36/37/38:  Irritating to eyes, respiratory system and skin 
The Safety Statements information of 3-METHYL-2-PYRAZOLIN-5-ONE(108-26-9):
24/25:  Avoid contact with skin and eyes 
RTECS: UQ9451500
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 108-26-9