Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
3-Thiopheneacetonitrile |
EINECS | 237-433-1 |
CAS No. | 13781-53-8 | Density | 1.171 g/cm3 |
PSA | 52.03000 | LogP | 1.81418 |
Solubility | N/A | Melting Point |
N/A |
Formula | C6H5NS | Boiling Point | 243.7 °C at 760 mmHg |
Molecular Weight | 123.178 | Flash Point | 92.4 °C |
Transport Information | UN 3276 6.1/PG 2 | Appearance | clear yellow to brown liquid |
Safety | 26-36/37-45-36/37/39 | Risk Codes | 20/21/22-36/37/38-23/24/25 |
Molecular Structure | Hazard Symbols | Xn, T | |
Synonyms |
3-Cyanomethylthiophene;3-Thienylacetonitrile; |
Article Data | 12 |
Conditions | Yield |
---|---|
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; bis(η3-allyl-μ-chloropalladium(II)) In 1,3,5-trimethyl-benzene at 20 - 140℃; for 5.16667h; Inert atmosphere; Sealed tube; chemoselective reaction; | 78% |
Conditions | Yield |
---|---|
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium carbonate In 1,4-dioxane; water at 100℃; for 12h; Inert atmosphere; Sealed tube; | 53% |
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium carbonate In 1,4-dioxane; water at 60℃; for 12h; Inert atmosphere; Sealed tube; |
Conditions | Yield |
---|---|
tetrabutylammomium bromide In dichloromethane; water Heating / reflux; | 44% |
With ethanol |
Conditions | Yield |
---|---|
With N-benzyl-N,N,N-triethylammonium chloride In water | 28% |
Conditions | Yield |
---|---|
With ethanol |
3-thiophene carboxaldehyde
[(p-methylphenyl)sulfonylmethyl]isonitrile
(thiophen-3-yl)acetonitrile
Conditions | Yield |
---|---|
With potassium tert-butylate 1.) THF, -20 deg C, 30 min, 2.) THF, -20 deg C, 30 min; Yield given. Multistep reaction; |
Methyl 2-cyano-2-(3-thienyl)acetate
(thiophen-3-yl)acetonitrile
Conditions | Yield |
---|---|
With water; triethylamine Product distribution; |
3-Methylthiophene
(thiophen-3-yl)acetonitrile
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 1 h / Reflux 2: tetrabutyl ammonium fluoride / acetonitrile; tetrahydrofuran / 0 - 20 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1: N-Bromosuccinimide; dibenzoyl peroxide 2: N-benzyl-N,N,N-triethylammonium chloride / water View Scheme |
3-Bromomethylthiophene
trimethylsilyl cyanide
(thiophen-3-yl)acetonitrile
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In tetrahydrofuran; acetonitrile at 0 - 20℃; Inert atmosphere; | 4.06 g |
(thiophen-3-yl)acetonitrile
N,N-dimethyl-formamide
Conditions | Yield |
---|---|
With 2,4-dichlorophenoxyacetic acid dimethylamine In toluene Heating; | 100% |