Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

4-(2-Aminopropyl)phenol

Related Products

Hot Products

Name

4-(2-Aminopropyl)phenol

EINECS 203-152-8
CAS No. 103-86-6 Density 1.07 g/cm3
PSA 46.25000 LogP 1.98220
Solubility N/A Melting Point 125-126 °C
Formula C9H13NO Boiling Point 279.2 °C at 760 mmHg
Molecular Weight 151.208 Flash Point 122.7 °C
Transport Information N/A Appearance white like or light brown crystalline powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 103-86-6 (4-(2-aminopropyl)phenol) Hazard Symbols N/A
Synonyms

Phenol,p-(2-aminopropyl)- (6CI,8CI);4-(2-Aminopropyl)phenol;4-Hydroxy-a-methylphenethylamine;4-Hydroxyamphetamine;DL-4-Hydroxyamphetamine;Hydroxyamfetamine;Hydroxyamphetamine;NSC 170995;Norveritol;Oxamphetamine;Paredrine;Paredrinex;Pulsoton;Racemic p-hydroxyamphetamine;dl-p-Hydroxyamphetamine;p-(2-Aminopropyl)phenol;p-Hydroxy-a-methylphenethylamine;p-Hydroxyamphetamine;p-Hydroxyphenylisopropylamine;a-Methyltyramine;

Article Data 22

4-(2-Aminopropyl)phenol Specification

The Phenol,4-(2-aminopropyl)-, with the CAS registry number 10199-50-5, is also known as D-4-Hydroxyamphetamine. Its EINECS number is 203-152-8. This chemical's molecular formula is C9H13NO and molecular weight is 151.21. What's more, its systematic name is 4-(2-aminopropyl)phenol. 

Physical properties of Phenol,4-(2-aminopropyl)- are: (1)ACD/LogP: 1.07; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.02; (4)ACD/LogD (pH 7.4): -1.56; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 12.47 Å2; (13)Index of Refraction: 1.562; (14)Molar Refractivity: 45.81 cm3; (15)Molar Volume: 141.2 cm3; (16)Polarizability: 18.16×10-24 cm3; (17)Surface Tension: 44.6 dyne/cm; (18)Density: 1.07 g/cm3; (19)Flash Point: 122.7 °C; (20)Enthalpy of Vaporization: 53.87 kJ/mol; (21)Boiling Point: 279.2 °C at 760 mmHg; (22)Vapour Pressure: 0.0024 mmHg at 25°C.

Preparation: this chemical can be prepared by p-Hydroxy-norephedrin-HCl at the ambient temperature and at the pressure of 3900.3. This reaction will need reagent H2 and solvents H2O, acetic acid, HClO4 with the reaction time of 14.5 hours. This reaction will also need catalyst 9.8percent Pd/C. The yield is about 68%.

Phenol,4-(2-aminopropyl can be prepared by p-Hydroxy-norephedrin-HCl.

Uses of Phenol,4-(2-aminopropyl)-: it can be used to produce N-Acetyl-p-hydroxyamphetamin at the ambient temperature. It will need solvent ethyl acetate with the reaction time of 30 min. The yield is about 91%.

Phenol,4-(2-aminopropyl)- and acetic acid anhydride can be used to produce N-Acetyl-p-hydroxyamphetamin

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: Oc1ccc(cc1)CC(N)C
(2)InChI: InChI=1/C9H13NO/c1-7(10)6-8-2-4-9(11)5-3-8/h2-5,7,11H,6,10H2,1H3
(3)InChIKey: GIKNHHRFLCDOEU-UHFFFAOYAW

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LDLo intravenous 100mg/kg (100mg/kg)   "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 101, 1948.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 103-86-6