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Cas Database

Name	4,6-dichloro-2-methylpyrimidine	EINECS	605-815-0
CAS No.	1780-26-3	Density	1.404 g/cm³
PSA	25.78000	LogP	2.09180
Solubility	N/A	Melting Point	41.5-45.5 °C(lit.)
Formula	C₅H₄Cl₂N₂	Boiling Point	210.8 °C at 760 mmHg
Molecular Weight	163.006	Flash Point	101.1 °C
Transport Information	UN 3261 8/PG 2	Appearance	white or offwhite crystalline powder
Safety	26-36/37/39-45	Risk Codes	34
Molecular Structure		Hazard Symbols	C
Synonyms	2-Methyl-4,6-dichloropyrimidine;NSC 35923;	Article Data	20

4,6-dichloro-2-methylpyrimidine Synthetic route

: 1194-22-5
2-methyl-4,6-dihydroxypyrimidine

: 1780-26-3
2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With trichlorophosphate Heating;	97%
With thionyl chloride In acetonitrile at 80℃; for 3h; Temperature; Concentration; Reagent/catalyst; Industrial scale;	94%
With trichlorophosphate at 95℃; for 18h;	90%

: 40497-30-1
2-methyl-1H-pyrimidine-4,6-dione

: 1780-26-3
2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With trichlorophosphate
With N,N-dimethyl-aniline; trichlorophosphate

: 4,6-Dichloro-2-methyl-1,2-dihydro-pyrimidine

: 1780-26-3
2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; diethyl ether for 0.0833333h; Ambient temperature; Yield given;

: 1780-26-3
2,4-dichloro-2-methylpyrimidine

Conditions

Conditions	Yield
With ammonia In methanol at 50℃; for 5h; Solvent; Temperature; Concentration; Industrial scale;	92%
With ammonium hydroxide In ethanol at 140℃; for 1h; Microwave irradiation;	90%
With ammonia In water; isopropyl alcohol regioselective reaction;	83%

4,6-dichloro-2-methylpyrimidine Chemical Properties

Synonyms: BUTTPARK 52\14-70;2-MDCP;2-METHYL-4,6-DICHLOROPYRIMIDINE;4,6-DICHLORO-2-METHYLPYRIMIDINE;4,6-Dichloro-2-methylpyrimidiine;Pyrimidine, 4,6-dichloro-2-methyl-;4,6-Dichloro-2-methylpyrimidine ,99%;4,6-Dichloro-2-Methylpyrimidine/2,4-dichloro-6-methylpyrimidine
The Molecular formula of 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3): C₅H₄Cl₂N₂
The Molecular Weight of 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):163
Molecular Structure :

Flash point:208 °F

4,6-dichloro-2-methylpyrimidine Safety Profile

Hazard Codes 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):

C
Risk Statements 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):
34: Causes burns
Safety Statements 4,6-DICHLORO-2-METHYLPYRIMIDINE(1780-26-3):
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
RIDADR:UN 3261 8/PG 2
WGK Germany:3
HazardClass:8
PackingGroup:III

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