Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

4-Aminophenol hydrochloride

Related Products

Hot Products

Name

4-Aminophenol hydrochloride

EINECS 200-122-6
CAS No. 51-78-5 Density 1.21g/cm3
PSA 46.25000 LogP 2.35760
Solubility soluble in water Melting Point 302 °C
Formula C6H7NO.HCl Boiling Point 282 °C at 760 mmHg
Molecular Weight 145.589 Flash Point 124.3 °C
Transport Information N/A Appearance Off white powder
Safety 28-36 Risk Codes 36/37/38-43
Molecular Structure Molecular Structure of 51-78-5 (4-Hydroxyaniline hydrochloride) Hazard Symbols IrritantXi
Synonyms

Phenol,4-amino-, hydrochloride (9CI);Phenol, p-amino-, hydrochloride (8CI);4-Hydroxyanilinium chloride;C.I. 76551;C.I.Oxidation Base 6A;Durafur Brown R;Fouramine CP;Fourrine 83;Fourrine P;Furro P;Futramine P;Pelagol CP;Pelagol Grey CP;Peltol P;p-Aminophenolhydrochloride;p-Hydroxyaniline hydrochloride;

Article Data 5

4-Aminophenol hydrochloride Synthetic route

100-02-7

4-nitro-phenol

51-78-5

p-aminophenol hydrochloride

Conditions
ConditionsYield
Stage #1: 4-nitro-phenol With sodium tetrahydroborate; water at 20℃; for 2h;
Stage #2: With hydrogenchloride In ethyl acetate
93%
7647-01-0

hydrogenchloride

2835-04-3

5-amino-2-hydroxybenzenesulfonic acid

51-78-5

p-aminophenol hydrochloride

Conditions
ConditionsYield
at 170℃; im geschlossenen Rohr;
7647-01-0

hydrogenchloride

78533-09-2

α-methylsuccinic di-p-anisidine

A

74-87-3

methylene chloride

B

498-21-5, 636-60-2

2-methylbutanedioic acid

C

51-78-5

p-aminophenol hydrochloride

Conditions
ConditionsYield
at 100℃;
123-30-8

4-amino-phenol

51-78-5

p-aminophenol hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol
108-95-2

phenol

51-78-5

p-aminophenol hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium azide / 5 h / 55 - 60 °C
2: hydrogenchloride / ethanol
View Scheme
3913-17-5

2-chloro-4,8-dimethyl-quinoline

51-78-5

p-aminophenol hydrochloride

1436858-68-2

4-(4,8-dimethylquinolin-2-ylamino)phenol hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water Heating;94%
51-78-5

p-aminophenol hydrochloride

404586-94-3

1-(tert-butoxy)-2-(tert-butoxy)carbonyl-1,2-dihydroisoquinoline

A

54840-15-2

4-N-tert-butoxycarbonylaminophenol

B

95932-40-4

tert-butyl (4-((tert-butoxycarbonyl)oxy)phenyl)carbamate

Conditions
ConditionsYield
In 1,2-dimethoxyethane at 20℃;A 93%
B n/a
In 1,2-dimethoxyethane at 20℃; for 16h;A 93%
B 5%
32314-39-9

4-chloro-2,8-dimethylquinoline

51-78-5

p-aminophenol hydrochloride

4-(2,8-dimethylquinolin-4-ylamino)phenol dihydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water for 10h; Heating;93%
3913-18-6

2-chloro-4,6-dimethylquinoline

51-78-5

p-aminophenol hydrochloride

1436858-62-6

4-(4,6-dimethylquinolin-2-ylamino)phenol hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol; water Heating;92%
51-78-5

p-aminophenol hydrochloride

22042-71-3

(4-formylphenoxy)acetic acid

96865-80-4

4-<<(4-hydoxyanilino)carbonyl>methoxy>benzaldehyde

Conditions
ConditionsYield
With TEA; dicyclohexyl-carbodiimide In tetrahydrofuran; N,N-dimethyl-formamide for 2h;89%

4-Aminophenol hydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

4-Aminophenol hydrochloride Specification

The CAS register number of 4-Aminophenol hydrochloride is 51-78-5. It also can be called as 4-Hydroxyaniline hydrochloride and the IUPAC name about this chemical is 4-aminophenol hydrochloride. The molecular formula about this chemical is C6H7NO.HCl and the molecular weight is 145.59 . Classification code about this chemical is Mutation data. This chemical can be used for the photographic imaging agent, synthetic dyes, fur dyes, etc. It is mainly used for fur dyeing, but also can be used for sulfur dyes and pharmaceutical intermediates. This chemical is stable, but it is hygroscopic, air and light sensitive. It is incompatible with strong oxidizing agents.

Physical properties about 4-Aminophenol hydrochloride are: (1)ACD/LogP: -0.29; (2)ACD/LogD (pH 5.5): -0.5; (3)ACD/LogD (pH 7.4): -0.29; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 10.29; (7)ACD/KOC (pH 7.4): 16.47; (8)#H bond acceptors: 2; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 2; (11)Polar Surface Area: 12.47Å2; (12)Flash Point: 124.3 °C; (13)Enthalpy of Vaporization: 54.17 kJ/mol; (14)Boiling Point: 282 °C at 760 mmHg; (15)Vapour Pressure: 0.00202 mmHg at 25°C.

Uses of 4-Aminophenol hydrochloride: it can be used to produce methyl-carbamic acid 4-amino-phenyl ester with methyl-carbamic acid methyl ester at temperature of 60 ℃. This reaction will need reagent POCl3 with reaction time of 10 hours. The yield is about 39%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin, it may cause sensitization by skin contact. When you are using it, wear suitable protective clothing. After contact with skin, wash immediately with plenty of soap-suds.

You can still convert the following datas into molecular structure:
(1)SMILES: Cl.Oc1ccc(N)cc1
(2)InChI: InChI=1/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H
(3)InChIKey: RVGOBWDGAVAVPJ-UHFFFAOYAR
(4)Std. InChI: InChI=1S/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H
(5)Std. InChIKey: RVGOBWDGAVAVPJ-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 750mg/kg (750mg/kg)   National Technical Information Service. Vol. AD691-490,

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 51-78-5