- 4-Hydroxy-2(5H)-furanone
- 4-Hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone
- 4-Hydroxy-2-(trifluoromethyl)benzoic acid
- 4-Hydroxy-2-(trifluoromethyl)benzonitrile
- 4-Hydroxy-2-(trifluoromethyl)phenylboronic acid
- 4-Hydroxy-2-(trifluoromethyl)pyrimidine
- 4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy
- 4-Hydroxy-2,3-dimethylbenzoic acid
- 4-Hydroxy-2,3-dimethyl-benzonitrile
- 4-Hydroxy-2,5-dimethyl-3(2H)furanone
- 3658-80-8Trisulfide, dimethyl
- 36588-75-7Cyclopentaneaceticacid, a-propyl-, ethyl ester
- 36589-29-4L-Arginine, ethylester, dihydrochloride (9CI)
- 3658-93-3Hexane, 1,1-diethoxy-
- 3658-95-5Butane, 1,1-diethoxy-
- 36589-61-41,4-Butanedisulfonicacid, sodium salt (1:2)
- 36590-19-91-Piperazinecarbothioamide,4-methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-
- 36590-52-0Benzenecarbohydrazonoylchloride, 4-chloro-N-phenyl-
- 36592-77-5Phenol,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2,3,6-trimethyl-, 1-acetate,hydrochloride (1:1)
- 36596-67-52,6-Dimethylbenzoic acid ethyl ester
Hot Products
- 365997-67-7Cyclohexanecarboxylic acid, 4-azido-3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (1S,3R,4S)-
- 36655-86-4POLYGLUCURONIC ACID
- 36671-85-9POLY(VINYL N-OCTADECYLCARBAMATE)
- 36673-16-2Titanium bis(triethanolamine)diisopropoxide
- 36692-27-0(2-Chlorophenyl)magnesium bromide
- 36725-37-86-(4-BROMOPHENYL)-4 5-DIHYDRO-2H-PYRIDA&
- 36727-29-43,5,5-Trimethylhexanoyl chloride
- 36747-44-1calcium p-toluenesulphonate
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
4-Hydroxy-2,5-dimethyl-3(2H)furanone |
EINECS | 222-908-8 |
| CAS No. | 3658-77-3 | Density | 1.249 g/cm3 |
| PSA | 46.53000 | LogP | 0.76370 |
| Solubility | 176g/L at 20℃ | Melting Point |
73-77 °C(lit.) |
| Formula | C6H8O3 | Boiling Point | 215.5 °C at 760 mmHg |
| Molecular Weight | 128.128 | Flash Point | 90.5 °C |
| Transport Information | N/A | Appearance | white to light yellow crystal powder |
| Safety | 36-24/25 | Risk Codes | 22 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
2,5-Dimethyl-3-hydroxy-4-oxo-4,5-dihydrofuran;2,5-Dimethyl-4,5-dihydrofuran-3-ol-4-one;2,5-Dimethyl-4-hydroxy-2,3-dihydrofuran-3-one;2,5-Dimethyl-4-hydroxy-3(2H)-furanone;4-Hydroxy-2,5-Dimethyl-3-oxo-2,3-dihydrofuran;4-Hydroxy-2,5-dimethyl-2,3-dihydrofuran-3-one;4-Hydroxy-2,5-dimethyl-2H-furan-3-one;Alletone;Furaneol;Pineapple ketone;3(2H)-Furanone,4-hydroxy-2,5-dimethyl-; |
Article Data | 10 |
4-Hydroxy-2,5-dimethyl-3(2H)furanone Synthetic route
- 3658-77-3
furaneol
| Conditions | Yield |
|---|---|
| With sulfuric acid at 10 - 20℃; for 1h; Reagent/catalyst; | 96.3% |
- 121063-57-8
glucofuraneol tetraacetate
A
- 3658-77-3
furaneol
B
- 121063-56-7
2,5-dimethyl-4-hydroxy-3<2H>-furanone β-D-glucopyranoside
| Conditions | Yield |
|---|---|
| With sodium methylate In methanol for 4h; Ambient temperature; | A 8% B 92% |
- 25566-16-9
hexane-3,4-cis-diol-2,5-dione
- 3658-77-3
furaneol
| Conditions | Yield |
|---|---|
| With sodium phosphate dibasic dodecahydrate; phosphoric acid In acetic acid butyl ester; water at 70 - 80℃; for 0.833333h; Reagent/catalyst; Flow reactor; | 86% |
| With disodium hydrogenphosphate; sodium hydrogencarbonate In water; ethyl acetate at 75℃; for 36h; pH=7; pH-value; Solvent; Temperature; Inert atmosphere; | 6.8 g |
| Conditions | Yield |
|---|---|
| With piperidine; acetic acid In ethanol at 80℃; for 24h; | 85% |
| Multi-step reaction with 3 steps 1: 90 percent / NaBH4 / H2O / 0.5 h / Ambient temperature 2: 95 percent / sorbitol dehydrogenase (SDH), NAD, α-ketoglutarate monosodium salt, (NH4)2SO4, GluDH / H2O / 10 h / pH 8.2 3: piperidine, glacial acetic acid / ethanol / 20 h / 80 °C View Scheme |
- 3658-77-3
furaneol
| Conditions | Yield |
|---|---|
| With oxalic acid for 5h; Heating; | 85% |
| Conditions | Yield |
|---|---|
| With hydrogenchloride; sodium hydroxide In water | 81.4% |
- 68786-17-4
ethyl 3,4-dihydroxy-5-methyl-2-furancarboxylate
- 3658-77-3
furaneol
| Conditions | Yield |
|---|---|
| With hydrogenchloride; sodium hydroxide In water; dimethyl sulfate | 76.6% |
- 111480-79-6
2,5-bisacetoxyhexane-3,4-dione
- 3658-77-3
furaneol
| Conditions | Yield |
|---|---|
| With oxalic acid In water for 3.2h; Heating; | 66% |
- 80037-18-9
2,2'-Dimethoxy-3,3'-dimethyl-[2,2']bioxiranyl
- 3658-77-3
furaneol
| Conditions | Yield |
|---|---|
| With sulfuric acid In methanol for 2h; Heating; | 59% |
| Conditions | Yield |
|---|---|
| With sodium dihydrogenphosphate; L-Lysine hydrochloride; sodium hydroxide In water at 110℃; for 0.75h; pH=6.5; Temperature; Concentration; | 56.7% |
4-Hydroxy-2,5-dimethyl-3(2H)furanone Chemical Properties
Molecular Structure of 4-Hydroxy-2,5-dimethyl-3(2H)furanone (CAS NO.3658-77-3):
.gif)
IUPAC Name: 4-Hydroxy-2,5-dimethylfuran-3-one
Canonical SMILES: CC1C(=O)C(=C(O1)C)O
InChI: InChI=1S/C6H8O3/c1-3-5(7)6(8)4(2)9-3/h3,8H,1-2H3
InChIKey: INAXVXBDKKUCGI-UHFFFAOYSA-N
Molecular Weight: 128.12592 [g/mol]
Molecular Formula: C6H8O3
XLogP3-AA: 0.7
H-Bond Donor: 1
H-Bond Acceptor: 3
EINECS: 222-908-8
storage temp.: 2-8 °C
Index of Refraction: 1.512
Molar Refractivity: 30.78 cm3
Molar Volume: 102.5 cm3
Surface Tension: 42.2 dyne/cm
Density: 1.249 g/cm3
Flash Point: 90.5 °C
Enthalpy of Vaporization: 52.55 kJ/mol
Boiling Point: 215.5 °C at 760 mmHg
Vapour Pressure: 0.032 mmHg at 25 °C
Appearance: white to light yellow crystal powder
Melting Point: 73-77 °C(lit.)
Classification Code: Mutation data
Product Categories: Furan&Benzofuran; API intermediates; Alphabetical Listings; C-D; Flavors and Fragrances; Furan flavors
4-Hydroxy-2,5-dimethyl-3(2H)furanone Uses
4-Hydroxy-2,5-dimethyl-3(2H)furanone (CAS NO.3658-77-3) is used as flavorant in the lields of food,beverage and daily-use chemical industry.
4-Hydroxy-2,5-dimethyl-3(2H)furanone Toxicity Data With Reference
| 1. | mmo-sat 2 mg/plate | CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. 22 (1988),85. | ||
| 2. | sce-mus-ipr 186 mg/kg | CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. 22 (1988),85. | ||
| 3. | orl-mus LD50:1608 mg/kg | CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. 22 (1988),85. |
4-Hydroxy-2,5-dimethyl-3(2H)furanone Consensus Reports
Reported in EPA TSCA Inventory.
4-Hydroxy-2,5-dimethyl-3(2H)furanone Safety Profile
Safety Information of 4-Hydroxy-2,5-dimethyl-3(2H)furanone (CAS NO.3658-77-3):
Hazard Codes:Xn 
Risk Statements:22
22:Harmful if swallowed
Safety Statements:36-24/25
36:Wear suitable protective clothing
24/25:Avoid contact with skin and eyes
WGK Germany:3
RTECS:LU3990000
F:10-23
Moderately toxic by ingestion. Mutation data reported. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating vapors.
4-Hydroxy-2,5-dimethyl-3(2H)furanone Standards and Recommendations
DOT Classification: 3; Label: Flammable Liquid
4-Hydroxy-2,5-dimethyl-3(2H)furanone Specification
4-Hydroxy-2,5-dimethyl-3(2H)furanone (CAS NO.3658-77-3), its Synonyms are 2,5-Dimethyl-3-hydroxy-4-oxo-4,5-dihydrofuran ; 2,5-Dimethyl-4-hydroxy-2,3-dihydrofuran-3-one ; 2,5-Dimethyl-4-hydroxy-3(2H)-furanone ; 3(2H)-Furanone, 4-hydroxy-2,5-dimethyl- ; Alletone ; FEMA No. 3174 ; Furaneol ; Pineapple ketone ; 3(2H)-Furanone, 2,5-dimethyl-4-hydroxy- ; 4-Hydroxy-2,5-dimethylfuran-2(3H)-one .
What can I do for you?
Get Best Price
