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4-NITROPHENYLARSONIC ACID

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4-NITROPHENYLARSONIC ACID

EINECS N/A
CAS No. 98-72-6 Density g/cm3
PSA 103.35000 LogP -0.32100
Solubility N/A Melting Point 300°C(lit.)
Formula C6H6 As N O5 Boiling Point 540.9°Cat760mmHg
Molecular Weight 247.039 Flash Point 243.3°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and As. See also ARSENIC COMPOUNDS and NITRO COMPOUNDS of AROMATIC HYDROCARBONS. Risk Codes 23/25-50/53
Molecular Structure Molecular Structure of 98-72-6 (P-NITROBENZENEARSONIC ACID) Hazard Symbols T,N
Synonyms

Arsonicacid, (4-nitrophenyl)- (9CI); Benzenearsonic acid, p-nitro- (6CI,7CI,8CI);(4-Nitrophenyl)arsonic acid; (p-Nitrophenyl)arsonic acid; 4-Nitrobenzenearsonicacid; Hep-a-Stat; Histostat; Histostat 50; NSC 5085; Nitarson; Nitarsone;p-Nitrobenzenearsonic acid

Article Data 15

4-NITROPHENYLARSONIC ACID Chemical Properties

IUPAC Name: (4-Nitrophenyl)arsonic acid
Synonyms: 4-Nitrobenzenearsonicacid ; Arsonicacid,4-nitrophenyl ; Hep-a-stat ; Histostat ; Histostat50 ; Nitarson ; P-nitro-benzenearsonicaci ; Ras-26
CAS NO: 98-72-6
Molecular Formula: C6H6AsNO5
Molecular Weight: 247.04
Molecular Structure:
EINECS: 202-695-8
Flash Point: 243.3 °C
Enthalpy of Vaporization: 86.16 kJ/mol
Melting point 2:98-300 °C (decomposition).
Boiling Point: 540.9 °C at 760 mmHg
Vapour Pressure: 1.56E-12 mmHg at 25°C
Merck : 13,6594
Appearance: 4-Nitrophenylarsonic acid (CAS NO.98-72-6) is pale yellow leaf-crystal.
Solubility: 4-Nitrophenylarsonic acid (CAS NO.98-72-6) is soluble in hot water and hot alcohol, very slightly soluble in cold water and cold alcohol.

4-NITROPHENYLARSONIC ACID Uses

 4-Nitrophenylarsonic acid (CAS NO.98-72-6) is used as pharmaceutical intermediates, but also an analytical reagent.

4-NITROPHENYLARSONIC ACID Production

 4-Nitrophenylarsonic acid (CAS NO.98-72-6) is derived by reaction of diazotization and arsenication of p-nitroaniline.
adding Nitroaniline into hydrochloric acid, stirring 2h, put ice cubes down to -5 °C,add sodium nitrite solution in 15min , stirring about 1h, obtaining diazonium salt solution. arsenic trioxide and sodium carbonate dissolved in water, cooling to 25 °C below, adding copper sulfate solution, and then adding the above-mentioned diazonium salt solution, the reaction temperature was controlled at 25°C below, generating 4-Nitrophenylarsonic acid (CAS NO.98-72-6) .

4-NITROPHENYLARSONIC ACID Toxicity Data With Reference

1.    

orl-rat LDLo:100 mg/kg

    NCNSA6    National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),13.
2.    

ivn-mus LD50:18 mg/kg

    CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#01192 .

4-NITROPHENYLARSONIC ACID Consensus Reports

Arsenic and its compounds are on the Community Right-To-Know List.

4-NITROPHENYLARSONIC ACID Safety Profile

RIDADR UN3465 6.1/PG 3

4-NITROPHENYLARSONIC ACID Standards and Recommendations

OSHA PEL: TWA 0.5 mg(As)/m3
ACGIH TLV: BEI: 35 µ (As)/L inorganic arsenic and methylated metabolites in urine

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