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| Name |
8-Hydroxy-7-iodo-5-quinolinesulfonic acid |
EINECS | 208-938-4 |
| CAS No. | 547-91-1 | Density | 2.193g/cm3 |
| PSA | 95.87000 | LogP | 2.87250 |
| Solubility | slight | Melting Point |
269-270 ºC |
| Formula | C9H6 I N O4 S | Boiling Point | N/A |
| Molecular Weight | 351.121 | Flash Point | N/A |
| Transport Information | UN 2585 | Appearance | yellow-green powder |
| Safety | Moderately toxic by ingestion, intravenous, and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx and SOx. Note: The name Anayodin is also used to designate sodium iodide. | Risk Codes | R34 |
| Molecular Structure |
|
Hazard Symbols |
|
| Synonyms |
5-Sulfo-7-iodo-8-hydroxyquinoline;5-Sulfo-7-iodo-8-quinolinol; 7-Iodo-5-sulfonic acid-8-hydroxyquinoline; 7-Iodo-8-hydroxylquinoline-5-sulfonicacid; 7-Iodo-8-hydroxyquinoline-5-sulfonic acid; 7-Iodo-8-quinolinol-5-sulfonicacid; 7-Iodooxine-5-sulfonic acid; 8-Hydroxy-7-iodoquinoline-5-sulfonic acid;Ferron; Ferron (analytical reagent); Loretin; Meditrene; NSC 3784; Quiniophen;Yellon |
8-Hydroxy-7-iodo-5-quinolinesulfonic acid Chemical Properties
Product Name: 7-Iodo-8-hydroyquinoline-5-sulfonic acid (CAS NO.547-91-1)
Molecular Formula: C9H6INO4S
Molecular Weight: 351.12g/mol
Mol File: 547-91-1.mol
Einecs: 208-938-4
Appearance: Yellow-green powder
Melting Point: 269-270 °C (dec.)(lit.)
Density: 2.193 g/cm3
Surface Tension: 87.7 dyne/cm
XLogP3-AA: 1.2
H-Bond Donor: 2
H-Bond Acceptor: 5
Product Categories: Haloquinolines; Hydroxyquinolines; Quinolines
8-Hydroxy-7-iodo-5-quinolinesulfonic acid Uses
7-Iodo-8-hydroyquinoline-5-sulfonic acid (CAS NO.547-91-1) is used for anti-amoebic drug. It belongs to halogenated 8 - hydroxy quinoline class. Such anti-amebic drugs by inhibiting the intestinal anti-amebic symbiotic bacteria play a role in production efficiency of amoebic dysentery, amoebic protozoa of the intestine had no effect outside. In recent years, foreign coverage of the drugs can cause subacute optic neuropathy, so the drug in Japan and the United States has been disabled.
8-Hydroxy-7-iodo-5-quinolinesulfonic acid Production
7-Iodo-8-hydroyquinoline-5-sulfonic acid (CAS NO.547-91-1) is by the 8 - hydroxyquinoline by oleum sulfonation, iodine tablets and iodized sodium hypochlorite derived.
8-Hydroxy-7-iodo-5-quinolinesulfonic acid Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 4gm/kg (4000mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 43, Pg. 495, 1954. | |
| rat | LDLo | intramuscular | 1gm/kg (1000mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 63, Pg. 122, 1938. | |
| rat | LDLo | intravenous | 500mg/kg (500mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 63, Pg. 122, 1938. | |
| rat | LDLo | oral | 800mg/kg (800mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 3, Pg. 44, 1948. |
8-Hydroxy-7-iodo-5-quinolinesulfonic acid Consensus Reports
Reported in EPA TSCA Inventory.
8-Hydroxy-7-iodo-5-quinolinesulfonic acid Safety Profile
Moderately toxic by ingestion, intravenous, and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx and SOx. Note: The name Anayodin is also used to designate sodium iodide.
Safety Information of 7-Iodo-8-hydroyquinoline-5-sulfonic acid (CAS NO.547-91-1):
Hazard Codes: C.gif){kind=small}
Risk Statements: 34
34: Causes burns
Safety Statements: 26-36/37/39-45
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
8-Hydroxy-7-iodo-5-quinolinesulfonic acid Specification
7-Iodo-8-hydroyquinoline-5-sulfonic acid ,its CAS NO. is 547-91-1,the synonyms is 5-Quinolinesulfonicacid,8-hydroxy-7-iodo- ; 8-Hydroxy-7-iodo-5-quinolinesulfonate ; 8-Hydroxy-7-iodo-5-quinolinesulfonicaci ; Ferron(analyticalreagent) ; Meditrene ; Quiniophen ; Yellon .
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