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Acetamide,N,N'-1,2-ethanediylbis-

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Name

Acetamide,N,N'-1,2-ethanediylbis-

EINECS 212-811-9
CAS No. 871-78-3 Density 1.033 g/cm3
PSA 58.20000 LogP 0.04040
Solubility 6.83E+05 mg/L at 25 °C Melting Point 170-172°C
Formula C6H12N2O2 Boiling Point 438.7 °C at 760 mmHg
Molecular Weight 144.173 Flash Point 214.8 °C
Transport Information N/A Appearance N/A
Safety 26-36/37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 871-78-3 (N,N'-DIACETYLETHYLENEDIAMINE) Hazard Symbols N/A
Synonyms

Acetamide,N,N'-ethylenebis- (7CI,8CI);1,2-Diacetamidoethane;1,2-Ethanediamine,N,N'-diacetyl-;Diacetylethylenediamine;N,N'-Diacetylethylenediamine;N,N'-Ethylenebisacetamide;N-[2-(Acetylamino)ethylene]acetamide;NSC 603;

Article Data 57

Acetamide,N,N'-1,2-ethanediylbis- Synthetic route

108-24-7

acetic anhydride

107-15-3

ethylenediamine

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
yttria-stabilized zirconia In acetonitrile for 2.5h; Heating;99%
With silica gel for 0.05h; Microwave irradiation; neat (no solvent);98%
With polydopamine sulfamic acid-functionalized silica gel nanocatalyst In neat (no solvent) at 20℃; for 0.2h;96%
13483-16-4

2,4,6-triacetyloxy-1,3,5-triazine

107-15-3

ethylenediamine

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
at 25℃; for 0.0833333h; neat (no solvent);99%
918-00-3

1,1,1-trichloroacetone

107-15-3

ethylenediamine

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
In hexane at 25℃;97%
64-19-7

acetic acid

107-15-3

ethylenediamine

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
at 80 - 160℃;93%
In water at 240 - 250℃; for 0.666667h;
With lithium chloride supported solid acid catalyst at 110 - 120℃; for 2h; Temperature; Large scale;
137465-85-1

1,8-bis(acetylamino)-3,6-diaza-4,5-dimethyl-3,5-octadiene

A

871-78-3

N,N'-diacetylethylenediamine

B

137465-87-3

1-isocyano-2-(N-acetylamino)-ethane

Conditions
ConditionsYield
With oxygen; rose bengal In acetonitrile at 13℃; for 11h; Irradiation;A 87%
B 87%
107-15-3

ethylenediamine

microgel-supported-CH3CO

microgel-supported-CH3CO

A

1001-53-2

monoacetylaminoethylamine

B

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
In tetrahydrofuran at 25℃; for 14h; Inert atmosphere;A 83.5%
B 9.9%
141-78-6

ethyl acetate

107-15-3

ethylenediamine

A

1001-53-2

monoacetylaminoethylamine

B

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
at 100℃; for 36h;A 81%
B n/a
at 20℃; for 6h;A 70%
B n/a
at 20℃;
at 100℃;
64-19-7

acetic acid

107-15-3

ethylenediamine

A

534-26-9

lysidine

B

1001-53-2

monoacetylaminoethylamine

C

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
With copper In benzene at 80℃; for 5h;A 74%
B n/a
C n/a
321746-35-4

C4H9ClN2O

1001-53-2

monoacetylaminoethylamine

A

1021441-10-0

1,2-bis(2-acetamidoethyl)-3-(acetamidomethyl)diaziridine

B

871-78-3

N,N'-diacetylethylenediamine

Conditions
ConditionsYield
With potassium carbonate In chloroform at 15℃; under 3750380 Torr; for 48h;A 57%
B n/a
107-15-3

ethylenediamine

603-69-0

ethyl 2-acetylacetoacetate

A

871-78-3

N,N'-diacetylethylenediamine

B

23652-55-3

ethyl (2Z)-3-[(2-{[(1Z)-3-ethoxy-1-methyl-3-oxoprop-1-enyl]amino}ethyl)amino]but-2-enoate

Conditions
ConditionsYield
In diethyl ether at 20℃;A 48%
B n/a

Acetamide,N,N'-1,2-ethanediylbis- Specification

This chemical is called Acetamide, N,N'-1,2-ethanediylbis-, and its systematic name is N,N'-Ethane-1,2-diyldiacetamide. With the molecular formula of C6H12N2O2, its molecular weight is 144.17. The CAS registry number of this chemical is 871-78-3.

Other characteristics of the Acetamide, N,N'-1,2-ethanediylbis- can be summarised as followings: (1)ACD/LogP: -2.01; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.01; (4)ACD/LogD (pH 7.4): -2.01; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1.92; (8)ACD/KOC (pH 7.4): 1.92; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 40.62 Å2; (13)Index of Refraction: 1.444; (14)Molar Refractivity: 37.09 cm3; (15)Molar Volume: 139.4 cm3; (16)Polarizability: 14.7×10-24cm3; (17)Surface Tension: 34 dyne/cm; (18)Density: 1.033 g/cm3; (19)Flash Point: 214.8 °C; (20)Enthalpy of Vaporization: 69.56 kJ/mol; (21)Boiling Point: 438.7 °C at 760 mmHg; (22)Vapour Pressure: 6.74E-08 mmHg at 25°C.

Production method of this chemical: The Acetamide, N,N'-1,2-ethanediylbis- could be obtained by the reactants of acetic acid anhydride and ethane-1,2-diamine. This reaction needs the catalyst of yttria-zirconia Lewis acidcatalyst, and the solvent of acetonitrile. The yield is 99 %. In addition, this reaction should be taken for 2.5 hours. The other condition is heating.

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin, so you should wear suitable protective clothing when you use it. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure: 
1.SMILES: O=C(NCCNC(=O)C)C
2.InChI: InChI=1/C6H12N2O2/c1-5(9)7-3-4-8-6(2)10/h3-4H2,1-2H3,(H,7,9)(H,8,10)
3.InChIKey: WNYIBZHOMJZDKN-UHFFFAOYAT

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