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Name |
Acetic acid,2-(2-chloroethoxy)- |
EINECS | 604-645-4 |
CAS No. | 14869-41-1 | Density | 1.296 g/cm3 |
PSA | 46.53000 | LogP | 0.32640 |
Solubility | N/A | Melting Point |
32.5-33.0 °C |
Formula | C4H7ClO3 | Boiling Point | 289.753 °C at 760 mmHg |
Molecular Weight | 138.551 | Flash Point | 129.038 °C |
Transport Information | N/A | Appearance | Brown crystal |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
Aceticacid, (2-chloroethoxy)- (8CI,9CI);1-Chloro-2-(carboxymethoxy)ethane;2-Chloroethoxyacetic acid;2-CHLOROETHOXY ACETIC ACID; |
Article Data | 16 |
1,4-dioxane
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With dipotassium peroxodisulfate; thionyl chloride at 25℃; for 4h; | 96.1% |
With hydrogenchloride; sodium hypochlorite |
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With hydrogenchloride; water for 2h; | 95% |
(2-chloro-ethoxy)-acetic acid ethyl ester
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With sodium hydroxide In tetrahydrofuran | 90% |
2-(2-Chloroethoxy)ethanol
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With chromium(VI) oxide; sulfuric acid In acetone at 0℃; for 6h; | 77% |
With sodium periodate; ruthenium trichloride In water; acetonitrile at 20℃; for 16h; | 74% |
Stage #1: 2-(2-Chloroethoxy)ethanol With calcium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate In dichloromethane; water at 20℃; for 0.5h; Stage #2: With sodium metabisulfite In dichloromethane; water | 72% |
2-chloroethyl cyanomethyl ether
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With hydrogenchloride |
carbon dioxide
(2-chloroethoxy)magnesium chloride
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
In tetrahydrofuran at -60℃; |
1-chloro-2-(2-nitro-ethoxy)-ethane
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With hydrogenchloride |
diethylene glycol
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With hydrogenchloride; sodium hypochlorite |
(2-chloroethoxy)-acetic acid
4-fluoro-2-methoxy-5-nitro-phenylamine
Conditions | Yield |
---|---|
With dmap; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide | 99% |
brecanavir
(2-chloroethoxy)-acetic acid
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide for 24h; | 92% |
The Acetic acid,2-(2-chloroethoxy)-, with the CAS registry number 14869-41-1, is also known as 2-(2-Chloroethoxy)acetic acid. This chemical's molecular formula is C4H7ClO3 and molecular weight is 138.5496. Its systematic name is called (2-chloroethoxy)acetic acid.
Physical properties of Acetic acid,2-(2-chloroethoxy)-: (1)ACD/LogP: -0.18; (2)ACD/LogD (pH 5.5): -2; (3)ACD/LogD (pH 7.4): -4; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 3; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 4; (11)Index of Refraction: 1.45; (12)Molar Refractivity: 28.739 cm3; (13)Molar Volume: 106.935 cm3; (14)Surface Tension: 41.367 dyne/cm; (15)Density: 1.296 g/cm3; (16)Flash Point: 129.038 °C; (17)Enthalpy of Vaporization: 58.21 kJ/mol; (18)Boiling Point: 289.753 °C at 760 mmHg; (19)Vapour Pressure: 0.001 mmHg at 25°C.
Preparation: this chemical can be prepared by 2-(2-chloro-ethoxy)-ethanol. This reaction will need reagents CrO3, H2SO4 and solvent acetone. The reaction time is 6 hours with reaction temperature of 0 °C. The yield is about 77%.
Uses of Acetic acid,2-(2-chloroethoxy)-: it can be used to produce 2-Chlor-aethoxyesssigsaeure-butylester at ambient temperature. This reaction will need reagent DCC, 4-N,N-dimethylaminopyridine and solvent CH2Cl2. The yield is about 91%.
You can still convert the following datas into molecular structure:
(1)SMILES: OC(=O)COCCCl
(2)InChI: InChI=1/C4H7ClO3/c5-1-2-8-3-4(6)7/h1-3H2,(H,6,7)
(3)InChIKey: MHXJETVNZPUVEN-UHFFFAOYAR