IUPAC Name: 2-Acetyloxybenzoic acid
Canonical SMILES: CC(=O)OC1=CC=CC=C1C(=O)O
InChI: InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
Molecular Formula: C₉H₈O₄
Molecular Weight: 180.16 g/mol
EINECS: 200-064-1
Classification Code: Analgesic; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Anti-inflammatory agents, non-steroidal; Antipyretic; Antirheumatic; Antirheumatic Agents; Cardiovascular Agents; Cyclooxygenase inhibitors; Drug / Therapeutic Agent; Enzyme Inhibitors; Fibrin Modulating Agents; Fibrinolytic agents; Hematologic Agents; Human Data; Mutation data; Peripheral Nervous System Agents; Platelet aggregation inhibitors; Reproductive Effect; Sensory System Agents
Stability: Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.
storage temp.: Store at RT.
solubility: H₂O: 10 mg/mL at 37 °C
Water Solubility: 3.3 g/L (20 °C)
Melting Point: 134-136 °C(lit.)
Index of Refraction: 1.55
Molar Refractivity: 44.52 cm³
Molar Volume: 139.5 cm³
Surface Tension: 49.8 dyne/cm
Density: 1.29 g/cm³
Flash Point: 131.2 °C
Enthalpy of Vaporization: 59.45 kJ/mol
Boiling Point: 321.4 °C at 760 mmHg
Vapour Pressure of Aspirin (CAS NO.50-78-2): 0.000124 mmHg at 25 °C

 Medicines containing derivatives of salicylic acid, structurally similar to aspirin, have been in medical use long long ago. Salicylate-rich willow bark extract became recognized for its specific effects on fever, pain and inflammation in the mid-eighteenth century. By the nineteenth century pharmacists were experimenting with and prescribing a variety of chemicals related to salicylic acid, the active component of willow extract.
French chemist Charles Frederic Gerhardt was the first to prepare acetylsalicylic acid in 1853,he mixed acetyl chloride with a sodium salt of salicylic acid ,during his work on the synthesis and properties of various acid anhydrides.A reaction ensued,the resulting melt  solidified quickly.So the compound was called "salicylic-acetic anhydride" by Gerhardt. But he did not pursue it further. In 1859, Von Gilm obtained analytically pure acetylsalicylic acid. In 1897,Bayer began selling aspirin around the world.

  Aspirin (CAS NO.50-78-2) is one of the most frequently used drugs in the treatment of mild to moderate pain, including that of migraines and fever.It is often combined with other non-steroidal anti-inflammatory drugs and opioid analgesics in the treatment of moderate to severe pain.In high doses, aspirin and other salicylates are used in the treatment of rheumatic fever, rheumatic arthritis, and other inflammatory joint conditions. In lower doses, aspirin (or its equivalents, e.g., carbasalate calcium) also inhibits platelet aggregation, and has been shown to reduce the incidence of transient ischemic attacks and unstable angina in men, and can be used prophylactically. It is also used in the treatment of pericarditis, coronary artery disease, and acute myocardial infarction.Low doses of aspirin are also recommended for the prevention of stroke, and myocardial infarction in patients with diagnosed cardiovascular disease. It is of no value in people without proven heart disease.

Hazard Codes: Xn
Risk Statements: 22-36/37/38 
R22: Harmful if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 1851
WGK Germany: 1
RTECS: VO0700000
PackingGroup: III

  Aspirin (CAS NO.50-78-2), its Synonyms are Acetylsalicylic acid ; 2-(Acetyloxy)benzoic acid ; 2-Acetoxybenzoic acid ; 2-Carboxyphenyl acetate ; Acesal ; Aceticyl ; Acetilsalicilico ; Acetilum acidulatum ; Benzoic acid, 2-(acetyloxy)- ; O-Acetylsalicylic acid ; Salicylic acid, acetate . It is odorless white crystals or crystalline powder with a slightly bitter taste.