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Balsalazide disodium

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Name

Balsalazide disodium

EINECS N/A
CAS No. 82101-18-6 Density N/A
PSA 154.31000 LogP 0.43180
Solubility N/A Melting Point N/A
Formula C17H15 N3 O6 . 2 Na Boiling Point N/A
Molecular Weight 401.28 Flash Point N/A
Transport Information N/A Appearance a stable, odorless orange to yellow microcrystalline powder, freely soluble in water and isotonic saline, sparingly soluble in methanol and ethanol, and practically insoluble in all other organic solvents.
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 82101-18-6 (Balsalazide disodium) Hazard Symbols N/A
Synonyms

Benzoicacid, 5-[[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, disodiumsalt (9CI); BX 661A

 

Balsalazide disodium Chemical Properties

Molecular Formula: C17H13N3Na2O6
Molar mass: 401.28 g/mol
Product categories of Balsalazide disodium (82101-18-6): API; digestive system drugs; Pharmaceutical and Biological Chemica
Structure of Balsalazide disodium (82101-18-6):

H-Bond Donor: 2
H-Bond Acceptor: 8
IUPAC Name: Disodium(3Z)-3-[[4-[(3-oxido-3-oxopropyl)carbamoyl]phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylate
Canonical SMILES: C1=CC(=CC=C1C(=O)NCCC(=O)[O-])NN=C2C=CC(=O)C(=C2)C(=O)[O-].[Na+].[Na+]
Isomeric SMILES: C1=CC(=CC=C1C(=O)NCCC(=O)[O-])N/N=C\2/C=CC(=O)C(=C2)C(=O)[O-].[Na+].[Na+]
InChI: InChI=1S/C17H15N3O6.2Na/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;/h1-6,9,19H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;/q;2*+1/p-2/b20-12-;; 
InChIKey: GNDOBTSWAIDUCE-OVVGNOJWSA-L

Balsalazide disodium Uses

 Balsalazide disodium (82101-18-6) is an anti-inflammatory drug used in the treatment of inflammatory bowel disease.

Balsalazide disodium Specification

 Balsalazide disodium (82101-18-6) also can be called Colazal ; BX 661A ; Benzoic acid, 5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-, disodium ; 5-[(E)-{4-[(2-carboxylatoéthyl)carbamoyl]phényl}diazényl]-2-hydroxybenzoate de disodium .It is usually administered as the disodium salt of Balsalazide . Balsalazide is sold in generic form in the US by several generic manufacturers, and also sold under the name "Colazal" in the US and "Colazide" in the UK.Its advantage over that drug in the treatment of Ulcerative colitis is believed to be the delivery of the active agent past the small intestine to the large intestine, the active site of ulcerative colitis.

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