- 25562-98-5Benzeneacetonitrile,2-phenoxy-
- 25563-02-4Benzeneacetic acid,2-phenoxy-
- 25563-04-62-(4-Chlorophenoxy)phenylacetic acid
- 25564-22-12-Cyclopenten-1-one,2-pentyl-
- 2556-46-9Benzenecarboximidamide,N,N'-diphenyl-
- 2556-53-8Methanol, calcium salt(2:1)
- 25566-04-53-phenylazetidin-3-ol
- 25567-10-6Benzoic acid, methyl-
- 2556-73-22H-Azepin-2-one,hexahydro-1-methyl-
- 25569-53-3POLY(ETHYLENE GLYCOL SUCCINATE)
Hot Products
- 25569-41-9poly-N(5)-(3-hydroxypropyl)-1-glutamine
- 255708-80-6255708-80-6
- 25573-59-5Hydrazine, tetrasilyl-
- 25586-20-32-Propenoic acid, polymer with butyl 2-propenoate and ethenylbenzene
- 25586-24-72-Propenoic acid, polymer with butyl 2-propenoate, ethenylbenzene and 2-propenamide
- 255881-94-8
- 25601-41-69-Decenoic acid, methyl ester
- 25608-64-41,1-Biphenyl-4,4-diol, polymer with 1,1-sulfonylbis4-chlorobenzene
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Bis(trimethylsilyl)trifluoroacetamide |
EINECS | 247-103-9 |
| CAS No. | 25561-30-2 | Density | 0.99 g/cm3 |
| PSA | 21.59000 | LogP | 3.63360 |
| Solubility | hydrolyses in water | Melting Point |
-10°C |
| Formula | C8H18F3NOSi2 | Boiling Point | 155 °C at 760 mmHg |
| Molecular Weight | 257.403 | Flash Point | 23.9 °C |
| Transport Information | UN 2924 3/PG 3 | Appearance | Clear to yellowish clear liquid |
| Safety | 26-36/37/39-45-16 | Risk Codes | 11-34-10-35-14 |
| Molecular Structure |
|
Hazard Symbols |
 T,  C,  F
|
| Synonyms |
Acetimidicacid, 2,2,2-trifluoro-N-(trimethylsilyl)-, trimethylsilyl ester (8CI);Silanol,trimethyl-, 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate (8CI);2,2,2-Trifluoro-N,O-bis(trimethylsilyl)acetamide;BSTFA;N,O-Bis(trimethylsilyl)trifluoracetamide;N,O-Bis(trimethylsilyl)trifluoroacetamide;NSC 379423;Trifluoro-N,O-bis(trimethylsilyl)acetamide; |
Article Data | 5 |
Bis(trimethylsilyl)trifluoroacetamide Synthetic route
- 354-32-5
trifluoracetyl chloride
- 1070-89-9
sodium hexamethyldisilazane
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 75-77-4
chloro-trimethyl-silane
- 354-38-1
2,2,2-trifluoroacetamide
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
| Conditions | Yield |
|---|---|
| With triethylamine | |
| With triethylamine |
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 63323-30-8, 55097-80-8, 58917-67-2, 58917-91-2, 60268-85-1, 60268-86-2, 63323-29-5, 63323-31-9, 63357-09-5, 64397-28-0, 64912-49-8, 64912-50-1, 82111-22-6
(+/-)-r-7,t-8-Dihydroxy-t-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene
- 64660-75-9, 134175-49-8
(+/-)-7β,8α-bis(trimethylsilyloxy)-9α,10α-epoxy-7,8,9,10-tetrahydrobenzopyrene
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide for 3h; Ambient temperature; | 100% |
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 103904-70-7
2-(o-chlorophenyl)-2-<(methoxycarbonyl)amino>-6-hydroxycyclohexanone
- 103904-71-8
[(1S,3S)-1-(2-Chloro-phenyl)-2-oxo-3-trimethylsilanyloxy-cyclohexyl]-carbamic acid methyl ester
| Conditions | Yield |
|---|---|
| With pyridine In dichloromethane for 1h; Heating; | 100% |
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
| Conditions | Yield |
|---|---|
| With pyridine at 25℃; for 44h; | 100% |
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 87751-69-7
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
- 108-59-8
malonic acid dimethyl ester
- 177468-91-6
(E)-dimethyl (1,3-diphenylprop-2-en-1-yl)propanedioate
| Conditions | Yield |
|---|---|
| With potassium acetate; bis(η3-allyl-μ-chloropalladium(II)) In tetrahydrofuran | 99% |
| With potassium acetate; bis(η3-allyl-μ-chloropalladium(II)) In dichloromethane | 98.9% |
| With lithium carbonate; bis(η3-allyl-μ-chloropalladium(II)) In toluene | 94% |
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 87751-69-7
rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene
- 108-59-8
malonic acid dimethyl ester
- 177468-91-6
(E)-dimethyl (1,3-diphenylprop-2-en-1-yl)propanedioate
| Conditions | Yield |
|---|---|
| bis(η3-allyl-μ-chloropalladium(II)) | 99% |
| bis(η3-allyl-μ-chloropalladium(II)) | 91% |
| bis(η3-allyl-μ-chloropalladium(II)) | 88% |
| bis(η3-allyl-μ-chloropalladium(II)) | 86% |
| bis(η3-allyl-μ-chloropalladium(II)) | 71% |
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 91003-20-2
(E)-2-(o-Chlorophenyl)-6-hydroxy-2-<(methoxycarbonyl)methylamino>cyclohexanone
- 91003-26-8
[(1S,3R)-1-(2-Chloro-phenyl)-2-oxo-3-trimethylsilanyloxy-cyclohexyl]-methyl-carbamic acid methyl ester
| Conditions | Yield |
|---|---|
| With pyridine In dichloromethane for 2h; Heating; | 96.5% |
- 663613-82-9
N-Boc-methylthiolincosamide
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 844504-73-0
C26H59NO7SSi4
| Conditions | Yield |
|---|---|
| With triethylamine In DMF (N,N-dimethyl-formamide) at 0 - 20℃; | 95% |
- 76644-52-5, 76704-31-9, 14447-34-8, 62247-41-0
rac-3-acetoxycyclohexene
- 25561-30-2
N,O-Bis(trimethylsilyl)trifluoroacetamide
- 108-59-8
malonic acid dimethyl ester
- 34939-28-1
dimethyl 2-(cyclohex-2-en-1-yl)malonate
| Conditions | Yield |
|---|---|
| bis(η3-allyl-μ-chloropalladium(II)) | 93% |
| bis(η3-allyl-μ-chloropalladium(II)) | 56% |
Bis(trimethylsilyl)trifluoroacetamide Chemical Properties
Molecular Formula: C8H18F3NOSi2
Molecular Weight: 257.4
Index of Refraction: 1.396
Molar Refractivity: 60.75 cm3
Molar Volume: 252.8 cm3
Surface Tension: 18.3 dyne/cm
Density: 1.018 g/cm3
Flash Point: 23 °C
Enthalpy of Vaporization: 40.64 kJ/mol
Boiling Point: 170 °C at 760 mmHg
Vapour Pressure: 1.5 mmHg at 25 °C
Melting point: -10 °C
Storage tempreture: 2-8 °C
Water solubility: Hydrolyses
Sensitive: Moisture sensitive
Appearance: Clear to yellowish clear liquid
Structure of Bis(trimethylsilyl)trifluoroacetamide (CAS NO.25561-30-2):
IUPAC Name: Trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate
Canonical SMILES: C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C
InChI: InChI=1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3
InChIKey: XCOBLONWWXQEBS-UHFFFAOYSA-N
Product Category of Bis(trimethylsilyl)trifluoroacetamide (CAS NO.25561-30-2): Analytical Chemistry;Biochemistry;GC Derivatizing Reagents;Reagents for Oligosaccharide Synthesis;Si (Classes of Silicon Compounds);Silylating Agents
Bis(trimethylsilyl)trifluoroacetamide Uses
Bis(trimethylsilyl)trifluoroacetamide (CAS NO.25561-30-2) can be used as pharmaceutical intermediate, neutral silylated protective agent, and is mainly used for synthesis of cephalosporin antibiotics.
Bis(trimethylsilyl)trifluoroacetamide Toxicity Data With Reference
Bis(trimethylsilyl)trifluoroacetamide (CAS NO.25561-30-2) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
Bis(trimethylsilyl)trifluoroacetamide Safety Profile
Hazard Codes: 
C,
F,
T
Risk Statements: 11-34-10-35-14
R10:Flammable.
R11:Highly flammable.
R14 :Reacts violently with water.
R34:Causes burns.
R35:Causes severe burns.
Safety Statements: 26-36/37/39-45-16
S16:Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Bis(trimethylsilyl)trifluoroacetamide Specification
Bis(trimethylsilyl)trifluoroacetamide , its cas register number is 25561-30-2. It also can be called N,O-Bis(trimethylsilyl)trifluoroacetamide ; Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate ; and BSTFA . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product: Do not induce vomiting. Get medical aid immediately. Notes to physician: Treat supportively and symptomatically.
In addition, Bis(trimethylsilyl)trifluoroacetamide (CAS NO.25561-30-2) is air sensitive and moisture sensitive. It is not compatible with strong oxidizing agents, acids, bases, and you must not take it with incompatible materials, ignition sources, exposure to air, exposure to moist air or water. And also prevent it to broken down into hazardous decomposition products: Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride gas, silicon dioxide.
What can I do for you?
Get Best Price
