100054-98-6

Basic information

• Product Name: 2-[(2-Methoxy-benzyl)-Methyl-aMino]-ethanol
• Synonyms: 2-[(2-Methoxy-benzyl)-Methyl-aMino]-ethanol;2-[(2-methoxyphenyl)methyl-methylamino]ethanol
• CAS NO: 100054-98-6
• Molecular Formula: C₁₁H₁₇NO₂
• Molecular Weight: 195.25818
• Mol File: 100054-98-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(2-Methoxy-benzyl)-Methyl-aMino]-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2-Methoxy-benzyl)-Methyl-aMino]-ethanol(100054-98-6)
• EPA Substance Registry System: 2-[(2-Methoxy-benzyl)-Methyl-aMino]-ethanol(100054-98-6)

Safety Data

• Hazardous Substances Data: 100054-98-6(Hazardous Substances Data)

Upstream product

• 6851-80-5 2-methoxy-N-methylbenzylamine 
• 107-07-3 2-chloro-ethanol 
• 67625-14-3 2-(2-Methoxy-phenyl)-3-methyl-oxazolidine 
• 135-02-4 ortho-anisaldehyde 
• 50-00-0 formaldehyd 
• 109926-15-0 N-(2-hydroxyethyl)-N-(2-methoxylbenzyl)amine 

Downstream Products

• 102451-22-9 3-{2-[(2-methoxy-benzyl)-methyl-amino]-ethoxy}-propionitrile 
• 1206549-03-2 N-(tert-butoxycarbonylmethyl)-N-(2-hydroxyethyl)-N-(2-methoxybenzyl)-N-methylammonium bromide 
• 106842-08-4 [2-(3-amino-propoxy)-ethyl]-(2-methoxy-benzyl)-methyl-amine 

Relevant articles and documents

Resolution of nitrogen-centered chiral tetraalkylammonium salts: application to [1,2] Stevens rearrangements with N-to-C chirality transmission

The resolution of N-chiral, amino acid-derived quaternary ammonium salts is demonstrated by using chiral BINOL as a complexing agent. Determination of the enantiopurities and absolute configurations of the resolved N-chiral tetraalkylammonium salts are described. The [1,2] Stevens rearrangement of N-chiral ammonium salts is shown to proceed with N-to-C chirality transmission to afford optically active 3-substituted morpholin-2-one derivatives.

Reductive Cleavage of N-Substituted 2-Aryl-1,3-oxazolidines: Generation of α-Amino-Substituted Carbanions

The behavior of several N-substituted 2-aryl-1,3-oxazolidines has been investigated under conditions of electron transfer from alkali metals in aprotic solvents.The reduction led to the regioselective cleavage of the benzylic carbon-oxygen bond, with formation of the corresponding N-substituted benzylamino alcohols in good yields.Investigation of the mechanism of this reductive cleavage, with the aid of labeling experiments, showed the intermediate formation of α-tertiary amino-substituted carbanions.