Preparation of Optically Active Piperazines from Ethyl (S)-2-(2-Alkyl-1-aziridinyl)acetates
Reaction of ethyl (S)-2-(2-alkyl-1-aziridinyl)acetates with boron trifluoride etherate in a large excess of ethylamine or ammonia gives the corresponding optically active piperazines in good yields.These piperazines retain the configuration of the starting aziridines.
Yahiro, Nobuhide,Ito, Shigekazu
p. 321 - 322
(2007/10/02)
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