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XL647 4-methylbenzenesulfonate is a chemical compound with significant pharmaceutical applications, characterized by its reversible and potent inhibitory effects on multiple receptor tyrosine kinases such as c-Met, VEGFR-2, and Ron. These kinases play a crucial role in cell growth, migration, and survival, and their dysregulation is linked to various cancers. XL647 4-methylbenzenesulfonate has demonstrated promising anti-cancer properties in preclinical studies, making it a candidate for further investigation in cancer therapy.

1000599-06-3

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1000599-06-3 Usage

Uses

Used in Pharmaceutical Industry:
XL647 4-methylbenzenesulfonate is used as a research compound for the development of cancer therapeutics due to its ability to inhibit receptor tyrosine kinases that are implicated in cancer progression.
Used in Cancer Therapy Research:
XL647 4-methylbenzenesulfonate is used as a potential anti-cancer agent for the treatment of solid tumors, given its demonstrated efficacy in preclinical studies. It is currently under investigation to explore its therapeutic potential and mechanism of action in clinical trials.
Used in Targeting Receptor Tyrosine Kinases:
In the field of oncology, XL647 4-methylbenzenesulfonate is used as a specific inhibitor targeting dysregulated receptor tyrosine kinases, which are often associated with the development and progression of various types of cancer. Its application aims to modulate these pathways and potentially halt or slow down cancer growth.

Check Digit Verification of cas no

The CAS Registry Mumber 1000599-06-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,5,9 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1000599-06:
(9*1)+(8*0)+(7*0)+(6*0)+(5*5)+(4*9)+(3*9)+(2*0)+(1*6)=103
103 % 10 = 3
So 1000599-06-3 is a valid CAS Registry Number.

1000599-06-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine,4-methylbenzenesulfonic acid

1.2 Other means of identification

Product number -
Other names 4-Quinazolinamine,N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-(((3aR,6aS)-octahydro-2-methylcyclopenta(c)pyrrol-5-yl)methoxy)-,4-methylbenzenesulphonate (1:1)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1000599-06-3 SDS

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