Three-component synthesis and anticancer evaluation of polycyclic indenopyridines lead to the discovery of a novel indenoheterocycle with potent apoptosis inducing properties
A multicomponent reaction of indane-1,3-dione, an aldehyde and an amine-containing aromatic compound leading to the formation of indenopyridine-based heterocyclic medicinal scaffolds has been investigated. It was found that the yields significantly improv
Manpadi, Madhuri,Uglinskii, Pavel Y.,Rastogi, Shiva K.,Cotter, Karen M.,Wong, Yin-Shan C.,Anderson, Lisa A.,Ortega, Amber J.,Van Slambrouck, Severine,Steelant, Wim F. A.,Rogelj, Snezna,Tongwa, Paul,Antipin, Mikhail Yu.,Magedov, Igor V.,Kornienko, Alexander
p. 3865 - 3872
(2008/10/09)
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