- BICYCLIC CARBOXAMIDE INHIBITORS OF KINASES
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Compounds of formula (I) or pharmaceutical acceptable salts are provided, wherein X1~X5, R1~R3, A, B, Z and n are defined in the description. And compositions containing said compounds, and the uses for inhibitors of kinases such as ALK, and the uses for treating cancer thereof are provided.
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Page/Page column 88
(2012/08/07)
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- HALO-SUBSTITUTED PYRIMIDODIAZEPINES
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The present invention provides PLK1 inhibitor compounds of formula I: useful in the treatment or control of cell proliferative disorders, particularly oncological disorders. These compounds and formulations containing such compounds may be useful in the treatment or control of solid tumors, such as, for example, breast, colon, lung and prostate tumors and other oncological diseases such as non-Hodgkin's lymphomas. Also provided are intermediate compounds useful in the synthesis of compounds of formula I.
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Page/Page column 9
(2009/12/28)
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- COMPOUNDS
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There is provided a compound of formula (I) or a pharmaceutically acceptable salt thereof. There is also provided a process for the manufacture of the compound of formula (I), and the use of the compound of formula (I) as a medicament and in the treatment
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Page/Page column 147
(2008/06/13)
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