Opioid Agonists an Antagonists. Peptides Containing N-Terminal Allyl Groups and/or a Thiomethylene Linkage in Place of a Peptide Bond
Peptides containing N-allyl or N,N-diallyl groups at the N-terminus have been synthesized as potential opioid antagonists.A number of analogues with an amine bond replaced by a thiomethylene group have also been prepared.In brain binding assays and in gui
Studies on analgesic oligopeptides. IV. Synthesis and analgesic activity of N-terminal shorter analogs of [D-Arg2]dermorphin and Des-Tyr1-dermorphin analogs