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100313-36-8

1-(benzyloxycarbonyl)-3-(4'-methoxybenzyl)carbodiimide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 100313-36-8 Structure

  • Basic information

    1. Product Name: 1-(benzyloxycarbonyl)-3-(4'-methoxybenzyl)carbodiimide
    2. Synonyms: 1-(benzyloxycarbonyl)-3-(4'-methoxybenzyl)carbodiimide
    3. CAS NO:100313-36-8
    4. Molecular Formula:
    5. Molecular Weight: 296.326
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 100313-36-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(benzyloxycarbonyl)-3-(4'-methoxybenzyl)carbodiimide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(benzyloxycarbonyl)-3-(4'-methoxybenzyl)carbodiimide(100313-36-8)
    11. EPA Substance Registry System: 1-(benzyloxycarbonyl)-3-(4'-methoxybenzyl)carbodiimide(100313-36-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 100313-36-8(Hazardous Substances Data)

100313-36-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 100313-36-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,1 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100313-36:
(8*1)+(7*0)+(6*0)+(5*3)+(4*1)+(3*3)+(2*3)+(1*6)=48
48 % 10 = 8
So 100313-36-8 is a valid CAS Registry Number.

100313-36-8Relevant articles and documents

A New and Efficient Synthesis of Guanosine

Groziak, Michael P.,Townsend, Leroy B.

, p. 1277 - 1282 (2007/10/02)

New methodology for the preparation of guanosine-type nucleoside analogues from o-amino carbamyl nucleoside precursors has been developed and is demonstrated by the three-step, high-yield synthesis of guanosine (16) from 5-amino-1-(β-D-ribofuranosyl)imidazole-4-carboxamide (1, AICA-riboside).Treatment of 1-(alkoxycarbonyl)-3-(arylmethyl)thioureas 8 with phosgene in the presence of triethylamine affords the highly electrophilic 1-(alkoxycarbonyl)-3-(arylmethyl)carbodiimide reagents 9 in high yield.These reagents are shown to condense with AICA-riboside readily at room temperature to afford N-acyl-N'-(arylmethyl)guanidino-substituted imidazole nucleoside derivatives.One of these derivatives, 5-(N-benzyl-N'-(ethoxycarbonyl)guanidino)-1-(β-D-ribofuranosyl)imidazole-4-carboxamide (11a), is smoothly debenzylated with cyclohexene in the presence of Pd(0) to afford 5-(N-(ethoxycarbonyl)guanidino)-1-(β-D-ribofuranosyl)imidazole-4-carboxamide (14).Prolonged heating of 14 in ethanol at reflux affords N-2-(ethoxycarbonyl)guanosine (15) in high yield.The ethoxycarbonyl protecting group of 15 is removed with concentrated NH4OH/pyridine to afford guanosine.This new methodology is much more efficient than those previously reported and should find application for the preparation of a wide variety of guanosine-type nucleoside analogues.

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