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1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid is a complex chemical compound characterized by a dihydroquinoline ring with a carboxylic acid group, a pyridine ring, and multiple fluorine atoms. The presence of the oxo group classifies it as a ketone. 1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid is notable for its potential pharmaceutical applications, as its structure includes features commonly found in drugs with antibacterial and antimalarial properties.

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  • 1,4-Dihydro-6,8-difluoro-1-ethyl-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid

    Cas No: 100325-51-7

  • USD $ 1.9-2.9 / Gram

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  • 100325-51-7 Structure
  • Basic information

    1. Product Name: 1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid
    2. Synonyms:
    3. CAS NO:100325-51-7
    4. Molecular Formula: C17H12F2N2O3
    5. Molecular Weight: 330.2856
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 100325-51-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 496.7°C at 760 mmHg
    3. Flash Point: 254.2°C
    4. Appearance: N/A
    5. Density: 1.424g/cm3
    6. Vapor Pressure: 1.11E-10mmHg at 25°C
    7. Refractive Index: 1.604
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid(100325-51-7)
    12. EPA Substance Registry System: 1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid(100325-51-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 100325-51-7(Hazardous Substances Data)

100325-51-7 Usage

Uses

Used in Pharmaceutical Industry:
1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid is used as a potential active pharmaceutical ingredient for the development of new drugs targeting bacterial infections and malaria. Its structural motifs suggest that it may possess the necessary properties to inhibit or kill these pathogens, although further research and testing are required to confirm its efficacy and safety.
Used in Drug Discovery Research:
In the field of drug discovery, 1-ethyl-6,8-difluoro-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid serves as a promising lead compound for the synthesis of novel antimicrobial and antimalarial agents. Its unique molecular structure provides a foundation for further chemical modifications and optimization to enhance its therapeutic potential and selectivity.

Check Digit Verification of cas no

The CAS Registry Mumber 100325-51-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,2 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 100325-51:
(8*1)+(7*0)+(6*0)+(5*3)+(4*2)+(3*5)+(2*5)+(1*1)=57
57 % 10 = 7
So 100325-51-7 is a valid CAS Registry Number.

100325-51-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-ethyl-6,8-difluoro-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 3-Quinolinecarboxylic acid,1,4-dihydro-6,8-difluoro-1-ethyl-4-oxo-7-(4-pyridinyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100325-51-7 SDS

100325-51-7Downstream Products

100325-51-7Relevant articles and documents

Process for the preparation of 3-(2'-fluorophenyl)pyridine

-

, (2008/06/13)

6-Fluoro-7-pyridylquinolone carboxylic esters and acids having antibacterial activity are prepared by coupling of a 2-fluorophenyl-metallic compound with a pyridyl bromide or iodide in the presence of a transition metal catalyst, nitrating and hydrogenati

7-heterocyclic-1,4-dihydroquinolones

-

, (2008/06/13)

1-Alkyl-6,8-difluoro-7-heterocyclic-1,4-dihydroquinol-4-one 3-carboxylic acids having antibacterial activity are prepared by conventional cyclization methods.

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