100377-16-0 Usage
Uses
Used in Chemical Synthesis:
N-(2-Cyano-1-cyclopenten-1-yl)-acetamide is used as an intermediate in the synthesis of various organic compounds. Its unique structure allows for further chemical modifications and reactions, making it a valuable building block in the development of new molecules with specific properties and applications.
Used in Pharmaceutical Industry:
N-(2-Cyano-1-cyclopenten-1-yl)-acetamide is used as a key component in the development of pharmaceuticals. Its reactivity and structural diversity make it a promising candidate for the creation of new drugs with potential therapeutic effects.
Used in Hydrogenation Processes:
N-(2-Cyano-1-cyclopenten-1-yl)-acetamide is used as a catalyst or reactant in the hydrogenation of β-acetylaminoacrylonitriles. This process is important in the production of various chemicals and materials, and the use of this compound can improve the efficiency and selectivity of the reaction.
Check Digit Verification of cas no
The CAS Registry Mumber 100377-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,7 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100377-16:
(8*1)+(7*0)+(6*0)+(5*3)+(4*7)+(3*7)+(2*1)+(1*6)=80
80 % 10 = 0
So 100377-16-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O/c1-6(11)10-8-4-2-3-7(8)5-9/h2-4H2,1H3,(H,10,11)
100377-16-0Relevant articles and documents
Copper-catalyzed oxidative ring closure of ortho-cyanoanilides with hypervalent iodonium salts: Arylation-ring closure approach to iminobenzoxazines
Aradi, Klra,Novk, Zoltn
, p. 371 - 376 (2015)
A novel, highly modular synthetic methodology with high functional group tolerance was developed for the construction of iminobenzoxazine derivatives from ortho-cyanoanilides and diaryliodonium triflates via an oxidative arylation-cyclization path. The reaction is supposed to involve the formation of highly active aryl-copper(III) species. In this novel transformation, copper(II) triflate was used as catalyst in 1,2-dichloroethane or ethyl acetate and the reaction takes place at 75 °C in 2-16 h.
Rhodium-catalyzed asymmetric hydrogenation of β-acetylamino acrylonitriles
Ma, Miaofeng,Hou, Guohua,Wang, Junru,Zhang, Xumu
experimental part, p. 506 - 511 (2011/06/17)
The rhodium-catalyzed asymmetric hydrogenation of β-acetylamino acrylonitriles was investigated by using monophosphine and bisphosphine ligands. It was found that an Rh-QuinoxP complex exhibited high enantioselectivities for β-aryl substituted β-acetylamino acrylonitriles and the Rh-JosiPhos CyPF-t-Bu complex was proven to be effective for the hydrogenation of tetrasubstituted olefins from cyclic β-acetylamino acrylonitriles.
