100414-80-0 Usage
Uses
Used in Pharmaceutical Industry:
Dan shen spiroketal lactone is used as a therapeutic agent for its anti-inflammatory, antioxidant, and anti-cancer properties, making it a valuable component in the development of treatments for various diseases.
Used in Cardiovascular Applications:
Dan shen spiroketal lactone is used as a cardioprotective agent for its ability to treat cardiovascular diseases, leveraging its traditional use and modern research findings.
Used in Neuroprotective Applications:
Dan shen spiroketal lactone is used as a neuroprotective agent to safeguard against neurodegenerative disorders, capitalizing on its historical use in traditional medicine and supported by scientific studies.
Used in Antioxidant Formulations:
Dan shen spiroketal lactone is used as an antioxidant in health supplements and pharmaceuticals to combat oxidative stress and related conditions.
Used in Anti-Diabetic Therapies:
Dan shen spiroketal lactone is used as an anti-diabetic agent to help manage diabetes, based on its potential effects on glucose metabolism and insulin sensitivity.
Used in Drug Development Research:
Dan shen spiroketal lactone is used as a subject of research in drug development for its diverse pharmacological activities and potential to contribute to new therapeutic agents for various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 100414-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,1 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 100414-80:
(8*1)+(7*0)+(6*0)+(5*4)+(4*1)+(3*4)+(2*8)+(1*0)=60
60 % 10 = 0
So 100414-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H16O3/c1-10-8-17(19-9-10)14-7-6-12-11(2)4-3-5-13(12)15(14)16(18)20-17/h3-7,10H,8-9H2,1-2H3/t10-,17?/m1/s1
100414-80-0Relevant articles and documents
Total synthesis of danshenspiroketallactone
Chorley, Daniel F.,Chen, Jack Li-Yang,Furkert, Daniel P.,Sperry, Jonathan,Brimble, Margaret A.
, p. 128 - 130 (2012/02/03)
Described herein is the first synthesis of the monobenz-annulated 5,5-spiroketals danshenspiroketallactone and epi-danshen-spiroketallactone, two components of the traditional Chinese medicine Danshen. Key features of the synthesis include a directed metallation-lactonisation sequence to install the isobenzofuranone moiety and an oxidative radical cyclisation to afford the monobenz-annulated 5,5-spiroketal. Georg Thieme Verlag Stuttgart. New York.
