100417-09-2Relevant articles and documents
The synthesis and some reactions OF 3-(2-aminophenyl)-2-iminothiazolidines. Ring closure of n-(2-thiocyanaoethyl,)-nphenylenediamines; thiazolidine vs. 3,1,6-benzothiadiazocine formation
Hornyak,Bertha,Zauer,Lempert,Feller,Pjeczka
, p. 2009 - 2030 (2007/10/02)
When treated with strong acids, the N-(2-thiocyanatoethyl)-n-phenylenediamines (1g-1y) are cyclized exclusively to 3-(2-aninophen- yl)-2-iminothiazolidines (6) while the related tertiary amines (1a-1f) gave, under the same conditions, benzothiadiazocines
Iminothiazolidine derivatives
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, (2008/06/13)
The invention relates to novel iminothiazolidine derivatives of the formula (I), STR1 wherein R1 and R3 represent, independently from each other, hydrogen or lower alkyl group, R3 is nitro or amino group, R stands for halo, lower alkyl, haloalkyl, nitro, amino, hydroxy, lower alkoxy, carboxy or lower alkoxycarbonyl group, and n is 0, 1 or 2, and pharmaceutically acceptable acid addition salts thereof. The iminothiazolidine derivatives of the formula (I) possess valuable antidepressant, antiparkinsonic, antiepileptic and spasmolytic activities.