10043-37-5

Basic information

• Product Name: 1-(piperidin-1-yl)prop-2-en-1-one
• Synonyms: 1-(Piperidin-1-yl)prop-2-en-1-one; 2-propen-1-one, 1-(1-piperidinyl)-
• CAS NO: 10043-37-5
• Molecular Formula: C₈H₁₃NO
• Molecular Weight: 139.1949
• Mol File: 10043-37-5.mol

Chemical Properties

• Boiling Point: 271.3°C at 760 mmHg
• Flash Point: 123.1°C
• Density: 0.991g/cm³
• Vapor Pressure: 0.00648mmHg at 25°C
• Refractive Index: 1.484
• CAS DataBase Reference: 1-(piperidin-1-yl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(piperidin-1-yl)prop-2-en-1-one(10043-37-5)
• EPA Substance Registry System: 1-(piperidin-1-yl)prop-2-en-1-one(10043-37-5)

Safety Data

• Hazardous Substances Data: 10043-37-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(piperidin-1-yl)prop-2-en-1-one is used as a synthetic chemical for the synthesis of various drugs and pharmaceutical products due to its unique chemical structure and properties.
Used in Flavoring Agents:
1-(piperidin-1-yl)prop-2-en-1-one is used as a flavoring agent in some food products, taking advantage of its strong odor.
Used in Antiviral and Antifungal Research:
1-(piperidin-1-yl)prop-2-en-1-one is studied for its potential pharmacological properties, including its antiviral and antifungal activities, although further research is needed to fully understand its potential applications and effects.

Upstream product

• 27161-21-3 1-hydroxy-1-piperidinocyclopropane 
• 71145-89-6 N-prop-2-ynylpiperidine N-oxide 

Downstream Products

• 117659-23-1 N-<2-iodo-3-(p-tolylsulphonyl)propionyl>piperidine 
• 94-62-2 Piperine 
• 117659-28-6 (E)-N-<3-(p-tolylsulphonyl)acryloyl>piperidine 
• 1375013-68-5 C₂₀H₂₇N₅O₂ 
• 1375013-69-6 C₂₁H₃₀N₅O₂⁽¹⁺⁾*I^(1-) 
• 1402416-38-9 2-(4-phenyl-2-tosyl-1,2-dihydrophthalazin-1-yl)-1-(piperidin-1-yl)ethanone 
• 1510826-38-6 2-(9-benzyl-9H-purin-6-yl)-4-phenyl-1-(piperidin-1-yl)butan-1-one 
• 1412411-07-4 (E)-7-hydroxy-2-(4-hydroxyphenyl)-3-(3-oxo-3-(piperidin-1-yl)prop-1-enyl)-4H-chromen-4-one 

Relevant articles and documents

Solvent-dependent competitive rearrangements of cyclic tertiary propargylamine N-oxides

In protic media, cyclic propargylamine N-oxides 1 undergo solvent-dependent competitive rearrangements leading to enamino aldehydes 5, acrylamides 3, and secondary amines 4. The ratios of the products are evaluated and the possible mechanism of the compet

Reaction of Cyclopropanamines with Hypochlorite

Ethylene was formed in 65percent yield when 1-(1-piperidino)cyclopropanol 6, was treated with hypochlorite.This observation raised the possibility that 1-aminocyclopropanecarboxylic acids (ACCs) could yield ethylene by a mechanism that involves (1) decarboxylation to a 1-aminocyclopropanol, followed by (2) a fragmentation of the carbinolamine to ethylene induced by a hypochlorite equivalent.Although this mechanism could be ruled out only for 1e, no evidence could be found for it in the reactions of other ACCs, 1a-f, with hypochlorite.The fact that 1b-cis-2,3-d2 yieldedonly ethylene-cis-1,2-d2 is consistent with either the mechanism described above or a nitrenium ion mechanism.In the reaction of cyclopropanamines with neutral hypochlorite, ethylene is not the major product.From the primary and secondary amino acids 1a-c, a 3-hydroxypropanenitrile or propanamide, 2a-c, probably the product of a nucleophilic ring-opening step followed by decarboxylation, is formed.Similar products are formed from other cyclopropanamines: 2a from 1g, 2d from 1h, 2e and 2f from 1i, and lactone 5 from 1j.