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CAS

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100432-06-2

(1-amino-2-propenyl)phosphonic acid, also known as alendronic acid, is a synthetic bisphosphonate medication that is used to treat and prevent osteoporosis in postmenopausal women and to increase bone mass in men with osteoporosis. It works by inhibiting bone resorption, making bones stronger and less likely to break.

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  • 100432-06-2 Structure

  • Basic information

    1. Product Name: (1-amino-2-propenyl)phosphonic acid
    2. Synonyms: (1-amino-2-propenyl)phosphonic acid
    3. CAS NO:100432-06-2
    4. Molecular Formula: C3H8 N O3 P
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 100432-06-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 353°Cat760mmHg
    3. Flash Point: 167.3°C
    4. Appearance: /
    5. Density: 1.422g/cm3
    6. Vapor Pressure: 6.25E-06mmHg at 25°C
    7. Refractive Index: 1.516
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: (1-amino-2-propenyl)phosphonic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: (1-amino-2-propenyl)phosphonic acid(100432-06-2)
    12. EPA Substance Registry System: (1-amino-2-propenyl)phosphonic acid(100432-06-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 100432-06-2(Hazardous Substances Data)

100432-06-2 Usage

Uses

Used in Pharmaceutical Industry:
(1-amino-2-propenyl)phosphonic acid is used as a medication for the treatment and prevention of osteoporosis in postmenopausal women and for increasing bone mass in men with osteoporosis. It is effective in inhibiting bone resorption, thereby strengthening bones and reducing the risk of fractures.
Used in Treatment of Paget's Disease of the Bone:
(1-amino-2-propenyl)phosphonic acid is used as a treatment for Paget's disease of the bone, a condition that causes bones to weaken and become more susceptible to fractures.
Used in Management of Hypercalcemia of Malignancy:
(1-amino-2-propenyl)phosphonic acid is used as a management option for hypercalcemia of malignancy, a condition where high levels of calcium in the blood are caused by cancer.
Used in Treatment of Other Bone-weakening Conditions:
(1-amino-2-propenyl)phosphonic acid is used as a treatment for other conditions that cause the bones to weaken, helping to improve bone strength and reduce the risk of fractures.

Check Digit Verification of cas no

The CAS Registry Mumber 100432-06-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,3 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100432-06:
(8*1)+(7*0)+(6*0)+(5*4)+(4*3)+(3*2)+(2*0)+(1*6)=52
52 % 10 = 2
So 100432-06-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H8NO3P/c1-2-3(4)8(5,6)7/h2-3H,1,4H2,(H2,5,6,7)

100432-06-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-aminoprop-1-en-2-ylphosphonic acid

1.2 Other means of identification

Product number -
Other names Phosphonic acid,(1-amino-2-propenyl)-(9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100432-06-2 SDS

100432-06-2Downstream Products

100432-06-2Relevant articles and documents

(1-Amino-2-propenyl)phosphonic acid, an Inhibitor of Alanine Racemase and D-Alanine:D-Alanine Ligase

Vo-Quang, Yen,Carniato, Denis,Vo-Quang, Liliane,Lacoste, Anne-Marie,Neuzil, Eugene,Goffic, Francois Le

, p. 579 - 581 (2007/10/02)

DL-(1-Amino-2-propenyl)phosphonic acid was synthesized through the sequential oxidation, sulfoxide elimination, and deprotection of diphenyl -3-(phenylthio)propyl>phosphonate.This analogue of vinylglycine is a strong inhibitor

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