1005291-43-9

Basic information

• Product Name: 2-Bromo-5-fluoro-4-formylpyridine
• Synonyms: 2-Bromo-5-fluoro-4-formylpyridine;4-Pyridinecarboxaldehyde, 2-bromo-5-fluoro-;2-Bromo-5-fluoroisonicotinaldehyde98%;2-Bromo-5-fluoro-4-pyridinecarboxaldehyde;2-bromo-5-fluoropyridine-4-carbaldehyde
• CAS NO: 1005291-43-9
• Molecular Formula: C₆H₃BrFNO
• Molecular Weight: 203.9965232
• Mol File: 1005291-43-9.mol

Chemical Properties

• Boiling Point: 251.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.778±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -3.62±0.18(Predicted)
• CAS DataBase Reference: 2-Bromo-5-fluoro-4-formylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-fluoro-4-formylpyridine(1005291-43-9)
• EPA Substance Registry System: 2-Bromo-5-fluoro-4-formylpyridine(1005291-43-9)

Safety Data

• Hazardous Substances Data: 1005291-43-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Bromo-5-fluoro-4-formylpyridine is utilized as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for a range of chemical reactions that can lead to the formation of complex molecules.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, 2-Bromo-5-fluoro-4-formylpyridine is used as a building block for the preparation of different pharmaceuticals. Its reactivity and the presence of multiple functional groups make it a valuable component in the development of new drugs.
Used in Fine Chemicals Production:
2-Bromo-5-fluoro-4-formylpyridine is also employed in the production of fine chemicals, which are high-purity chemicals used in various applications, including the synthesis of specialty materials and the formulation of high-value products.
Storage and Safety:
It is essential to store 2-Bromo-5-fluoro-4-formylpyridine in a cool, dry place in a tightly closed container to ensure its stability and prevent degradation. Due to its potential hazardous effects, it is crucial to handle this chemical with appropriate protective measures, including the use of protective clothing, gloves, and eye/face protection.

Upstream product

• 41404-58-4 2-bromo-5-fluoropyridine 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 2201097-16-5 N-(5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl)benzamide 
• 1883426-16-1 5-bromo-1H-pyrazolo[3,4-c]pyridin-3-ylamine 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES

Provided herein are Heterocyclic compounds of formula (I): and pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof, wherein W, X, Y, R1, R2, and RN are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound, and methods for treating or preventing animal and human filarial worm infections and diseases.

BICYCLIC PROLINE COMPOUNDS

The invention is concerned with the compounds of formula (I) and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

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The invention provides a neurotrophic factor tyrosine kinase receptor inhibitor. The tyrosine kinase receptor inhibitor provided by the invention has a tricyclic parent core structure, can inhibit theactivity of Trk kinase and can be used for treating mammalian diseases mediated by the Trk kinase.

1-(HET)ARYLSULFONYL-(PYRROLIDINE OR PIPERIDINE)-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS

The invention is concerned with the compounds of formula I and salts thereof and other compounds of formulas II-IX as disclosed herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formulas I-IX as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain or asthma.

SPIRO CONDENSED BARBITURIC ACID DERIVATIVES FOR USE AS ANTIBACTERIAL

In one aspect, the present invention relates to compounds of Formula (I): to pharmaceutically acceptable salts thereof, to methods of using them to treat bacterial infections, and to method for their preparation.