1005397-62-5

Basic information

• Product Name: 2,6-DIMETHYLPIPERIDIN-4-ONE HYDROCHLORIDE
• Synonyms: 2,6-DIMETHYLPIPERIDIN-4-ONE HYDROCHLORIDE;2,6-Dimethylpiperidin-4- onehydrochloride (mixture of cis- andtrans-);6-diMethylpiperidin-4-one hydrochloride;2,6-DIMETHYLPIPERIDIN-4-ONE HCL
• CAS NO: 1005397-62-5
• Molecular Formula: C7H14ClNO
• Molecular Weight: 163.64516
• Mol File: 1005397-62-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2,6-DIMETHYLPIPERIDIN-4-ONE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIMETHYLPIPERIDIN-4-ONE HYDROCHLORIDE(1005397-62-5)
• EPA Substance Registry System: 2,6-DIMETHYLPIPERIDIN-4-ONE HYDROCHLORIDE(1005397-62-5)

Safety Data

• Hazardous Substances Data: 1005397-62-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2,6-Dimethylpiperidin-4-one hydrochloride is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its ability to be incorporated into the molecular structures of these compounds makes it a valuable component in the development of new drugs and agricultural products.
Used in Rubber Chemicals Manufacturing:
In the rubber industry, 2,6-dimethylpiperidin-4-one hydrochloride is utilized in the production of rubber chemicals. Its presence in these chemicals contributes to the enhancement of rubber properties, such as durability and resistance to environmental factors.
Used in Dye Production:
2,6-Dimethylpiperidin-4-one hydrochloride is also employed in the manufacturing of dyes. Its chemical properties allow it to be integrated into dye molecules, resulting in the creation of a wide range of colors and shades for various applications.
Used as a Catalyst in Chemical Reactions:
Furthermore, 2,6-dimethylpiperidin-4-one hydrochloride serves as a catalyst in numerous chemical reactions. Its catalytic properties enable it to accelerate reaction rates and improve the efficiency of various chemical processes, making it an essential component in the field of organic chemistry.

Upstream product

• 1309479-07-9 dimethyl (2R,6S)-4,4-dihydroxy-2,6-dimethyl-piperidinium-3,5-dicarboxylate hydrobromide 
• 15409-98-0 2,6-dimethyl-4-oxo-piperidine-3,5-dicarboxylic acid diethyl ester 

Downstream Products

• 184368-70-5 2,6-dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 184368-70-5 2,6-dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 604010-24-4 tert-butyl 2,6-dimethyl-4-oxopiperidine-1-carboxylate 

Relevant articles and documents

4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-3,6-DIHYDROPYRIDINE-1-(2H)-CARBOXAMIDE DERIVATIVES AS LIMK AND/OR ROCK KINASES INHIBITORS FOR USE IN THE TREATMENT OF CANCER

The present invention concerns a compound of formula (I), in particular as LIMK and/or ROCK kinases inhibitors. The present invention also concerns these new inhibitors for use for the treatment of a condition selected in the group consisting of: cancers, virion infections, ocular hypertension and glaucoma formation, Neurofibromatosis type 1 and 2, psoriatic lesions, inflammatory diseases and hyperalgesia, central sensitization and chronic pain, reproduction erectile dysfunction, and neuronal diseases. The present description discloses the syntheses and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 32 to 127; examples 1 to 96; families 1 to 8; compounds; biological studies; tables). An exemplary compound is e.g. 4-(5-m ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N-phenyl-3,6-dihydropyridine-1-(2H)-carboxamide (example 1; compound 5).

Piperidone derivatives and medical uses thereof

The present invention relates to compositions comprising 4-Oxo-piperidine-carboxylates and derivatives thereof, for example derivatives substituted with phenyl, nitrophenyl or benzyl groups. It also teaches the medical use of these and related compounds for treatment of retroviral diseases, in particular, HIV and HTLV, proliferative diseases, in particular CML and Trypanosomiasis.

UROTENSIN II RECEPTOR ANTAGONISTS

The invention is directed to Urotensin II receptor antagonists. More specifically, the present invention relates to certain novel compounds and methods for preparing compounds, compositions, intermediates and derivatives thereof. Pharmaceutical compositio

In search of novel agents for therapy of tropical diseases and human immunodeficiency virus

Malaria, sleeping sickness, Chagas' disease, Aleppo boil, and AIDS are among the tropical diseases causing millions of infections and cases of deaths per year because only inefficient chemotherapy is available. Since the targeting of the enzymes of the polyamine pathway may provide novel therapy options, we aimed to inhibit the deoxyhypusine hydroxylase, which is an important step in the biosynthesis of the eukaryotic initiation factor 5A. In order to identify new lead compounds, piperidines were produced and biologically evaluated. The 3,5-diethyl piperidone-3,5-dicarboxylates 11 and 13 substituted with 4-nitrophenyl rings in the 2 and 6 positions were found to be active against Trypanosoma brucei brucei and Plasmodium falciparum combined with low cytotoxicity against macrophages. The corresponding monocarboxylates are only highly active against the T. brucei brucei. The piperidine oximether 53 demonstrated the highest plasmodicidal activity. Moreover, compounds 11 and 53 were also able to inhibit replication of HIV-1.