100668-10-8Relevant articles and documents
Electrochemical oxidation of caffeic and ferulic acid derivatives in aprotic medium
Salas-Reyes, Magali,Herna?ndez, Javier,Domi?nguez, Zaira,Gonza?lez, Felipe J.,Astudillo, Pablo D.,Navarro, Rosa Elena,Marti?nez-Benavidez, Evelin,Vela?zquez-Contreras, Carlos,Cruz-Sa?nchez, Samuel
, p. 693 - 701 (2011)
We studied the electrochemical behaviour as a function of the structure of a series of caffeic and ferulic acids derivatives as well as their corresponding redox moieties catechol and guaiacol by cyclic voltammetry. Results revealed that the medium is key
Host-guest complexation of antioxidative caffeic and ferulic acid amides with a functionalized cyclophane
Virues, Claudia,Dominguez, Zaira,Salas, Magali,Navarro, Rosa Elena,Velazquez, Enrique F.,Cruz, Samuel,Hernandez, Javier,Inoue, Motomichi
, p. 407 - 413 (2012)
Host-guest complexation has been studied by 1H NMR on the benzyl and phenethyl amides of ferulic and caffeic acids as the guests in chloroform and acetonitrile; the counter host is a cyclophane which integrates four phenylene rings, amino and a
Synthesis and structure-activity relationship analysis of caffeic acid amides as selective matrix metalloproteinase inhibitors
Shi, Zhi-Hao,Li, Nian-Guang,Shi, Qian-Ping,Tang, Hao,Tang, Yu-Ping,Li, Wei,Yin, Lian,Yang, Jian-Ping,Duan, Jin-Ao
, p. 1206 - 1211 (2013/03/14)
Four series of acid amides were synthesized, and through measurement using a fluorogenic substrate assay with human recombinant MMP-1, MMP-2 and MMP-9, compound 3f showed considerable inhibitory activities against MMP-2, MMP-9 and the best selectivity over MMP-1. Preliminary structure-activity relationship analysis indicated that caffeic acid amides with electron-donating groups at para-position of amino phenyl group showed better inhibitory activities and selectivity than those with electron-withdrawing groups, and the presence of adjacent dihydroxy in the caffeoyl group was very important for the MMP-2 and MMP-9 inhibitory activities.
CATECHOL-BASED DERIVATIVES FOR TREATING OR PREVENTING DIABETICS
-
Page/Page column 4; 6, (2009/06/27)
The present invention provides a catechol-based derivative and a pharmaceutical acceptable salt therefrom and a solvate therefrom. A pharmaceutical composition for preventing or treating diabetics and ischemics, comprising a catechol-based derivative of formula (I) and at least one selected from the group consisting of a pharmaceutical excipient, a diluent and a carrier.