- MONOCARBOXYLIC ACID TRANSPORTER 4 (MCT4) MODULATORS AND USES THEREOF
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Disclosed herein are compounds, compositions, and methods for modulating the monocarboxylic acid transporter 4 (MCT4) with the compounds and compositions disclosed herein. Also described are methods of treating diseases or conditions that are mediated by
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- 1,4,5,6-Tetrahydropyridazines by Cycloaddition of Enol Ethers to Azoalkenes and their Aromatisation to Pyridazines.
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Transient azoalkenes generated from acyl- and 4-tolylsulphonyl-hydrazones of α-haloacetophenones and of ethyl bromopyruvate are intercepted by cycloaddition to enol ethers, giving 6-alkoxy-1,4,5,6-tetrahydropyridazines (2). 6-Alkoxy-3-aryl-1,4,5,6-tetrahydropyridazines are converted by reaction with sodium ethoxide into 3-arylpyridazines (3).
- Clarke, Simon J.,Gilchrist, Thomas L.
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p. 3371 - 3389
(2007/10/02)
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