100784-98-3

Basic information

• Product Name: 3,5-DIPHENYL-1H-PYRROLE-2-CARBOXYLIC ACID
• Synonyms: 3,5-DIPHENYL-1H-PYRROLE-2-CARBOXYLIC ACID
• CAS NO: 100784-98-3
• Molecular Formula: C₁₇H₁₃NO₂
• Molecular Weight: 263.29
• Mol File: 100784-98-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-DIPHENYL-1H-PYRROLE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIPHENYL-1H-PYRROLE-2-CARBOXYLIC ACID(100784-98-3)
• EPA Substance Registry System: 3,5-DIPHENYL-1H-PYRROLE-2-CARBOXYLIC ACID(100784-98-3)

Safety Data

• Hazardous Substances Data: 100784-98-3(Hazardous Substances Data)

Usage

Uses

3,5-Diphenyl-1H-pyrrole-2-carboxylic Acid is a useful intermediate for organic synthesis. It is used in the preparation of pyrrolecarboxylates.

Upstream product

• 91307-93-6 3,5-diphenyl pyrrole-1,2-dicarboxylate de diethyle 
• 5153-67-3 nitrostyrene 
• 40682-54-0 ethyl N-benzylideneglycinate 
• 65939-64-2 (±)-diethyl 3,5-diphenyl-3,4-dihydro-2H-pyrrole-2,2-dicarboxylate 
• 94-41-7 benzalacetophenone 
• 1292310-23-6 methyl 2,5-dioxo-3,5-diphenylpentanoate 
• 89649-52-5 3,5-diphenylpyrrole-2-carboxylate de methyle 

Downstream Products

• 943817-33-2 C₂₄H₂₆N₂O₃ 
• 3274-56-4 2,4-diphenylpyrrole 

Relevant articles and documents

A new synthesis of pyrrole-2-carboxylic acids

A new two-step synthesis of pyrrole-2-carboxylic acids is described, steps via 1,3 dipolar cycloaddition of azomethine ylides to nitro-styrenes and oxidation of the resulting pyrrolidines with alkaline hydrogen peroxide.

Synthesis of 2,2′-dipyrryl ketones from pyrrole-2-carboxylic acids with trifluoroacetic anhydride

An efficient synthesis of 2,2′-dipyrryl ketones has been carried out from pyrrole-2-carboxylic acids using trifluoroacetic anhydride (TFAA). Simultaneous generation of both mixed anhydride and 2-unsubstituted pyrrole, via facile decarboxylation with in-si

A new synthesis of 3,5-diaryl-pyrrole-2-carboxylic acids and esters

A new two-step synthesis of pyrrole-2-carboxylic acids, steps via 1,3 dipolar cycloaddition of azomethine ylides to nitro-styrenes and oxidation of the resulting pyrrolidines with alkaline hydrogen peroxide is described. The oxidation of cycloadducts 3 by the means of MnO2 under different conditions also has been examined. (C) 2000 Elsevier Science Ltd.

The Synthesis and Chemistry of Azolenines. Part 4. Preparation and Rearrangement of some 3,5-Diaryl-2H-pyrrole-2,2-dicarboxylic Esters

Oxidation of diethyl 3,5-diaryl-3,4-dihydro-2H-pyrrole-2,2-dicarboxylates (3) with chloranil in refluxing xylene gives not the 3,5-diaryl-2H-pyrrole-2,2-dicarboxylates (4) as reported by an earlier group, but instead the rearranged, isomeric, 1H-pyrrole-1,2-dicarboxylates (5). 2H-Pyrroles (4) may be obtained from the dihydropyrroles (3) using DDQ in benzene at room temperature; they rearrange to the isomers (5) in boiling xylene via an acyl -sigmatropic shift from carbon to nitrogen, a novel process in the 2H-pyrrole series.Thermal analyses indicate that the rearrangement is concerted with negligible charge separation in the transition state.Other novel 3,5-diaryl-1H-pyrrole-2-carboxylic acid derivatives are described.