100872-42-2

Basic information

• Product Name: 2-(Benzylsulfonyl)-1{H}-benzimidazole
• Synonyms: 2-(Benzylsulfonyl)-1{H}-benzimidazole
• CAS NO: 100872-42-2
• Molecular Formula: C₁₄H₁₂N₂O₂S
• Molecular Weight: 272.33
• Mol File: 100872-42-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(Benzylsulfonyl)-1{H}-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Benzylsulfonyl)-1{H}-benzimidazole(100872-42-2)
• EPA Substance Registry System: 2-(Benzylsulfonyl)-1{H}-benzimidazole(100872-42-2)

Safety Data

• Hazardous Substances Data: 100872-42-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(Benzylsulfonyl)-1H-benzimidazole is used as a pharmaceutical intermediate for the synthesis of various organic compounds. Its role in the industry is crucial for creating new drug molecules that can address a range of health conditions.
Used in Medicinal Chemistry Research:
2-(Benzylsulfonyl)-1H-benzimidazole is used as a research compound for exploring its potential anti-cancer and anti-inflammatory properties. Its study contributes to the advancement of knowledge in medicinal chemistry and the development of new therapeutic strategies.
Used in Drug Development:
2-(Benzylsulfonyl)-1H-benzimidazole is employed as a key component in the development of pharmaceutical drugs. Its biological activity makes it a valuable compound for creating new medications that can treat various diseases and disorders.

Upstream product

• 104340-32-1 (benzimidazol-2-yl) benzyl sulfoxide 
• 100-44-7 benzyl chloride 
• 583-39-1 2,3-dihydrobenzimidazol-2-thione 
• 51290-77-8 2-(benzylthio)-1H-benzo[d]imidazole 

Downstream Products

• 102311-51-3 1-benzyl-2-(benzylsulfonyl)-1H-benzo-[d]-imidazole 
• 100969-47-9 2-(benzylsulfonyl)-1-methyl-1H-benzo[d]imidazole 

Relevant articles and documents

Reusable BNPs-SiO2@(CH2)3NHSO3H-catalysed selective oxidation of sulfides to sulfones

Reusable boehmite nanoparticles–silica–NHSO3H (BNPs-SiO2@(CH2)3NHSO3H) was found to be an efficient heterogeneous nanocatalyst for the selective oxidation of sulfides to sulfones in the presence of H2O2. Excellent yields, easy and quick isolation of products, short reaction times and excellent selectivity are the main advantages of this method. The catalyst was characterized using Fourier transform infrared spectroscopy, energy-dispersive X-ray analysis, X-ray diffraction, and transmission and scanning electron microscopies.

Fe3O4?BNPs?SiO2-SO3H as a highly chemoselective heterogeneous magnetic nanocatalyst for the oxidation of sulfides to sulfoxides or sulfones

To achieve green chemistry goals and also to reduce the cost of catalysts as well as to avoid producing toxic wastes and show the importance of separation and recycling of catalysts from the reaction medium, in this work, we describe the preparation and characterization of magnetic acidic boehmite nanoparticles as a heterogeneous catalyst, which is called Fe3O4?BNPs?SiO2-SO3H. This catalyst works efficiently in the selective oxidation of sulfides to sulfoxides or sulfones in the presence of H2O2 as a green oxidant. It can easily be separated from the reaction medium by using an external magnet and it was recycled 6 times without loss of magnetic catalytic properties.

Host (aluminum incorporated mesocellulous silica foam (Al-MCF))-guest (tungsten polyoxometalate) nanocomposite material: An efficient and reusable catalyst for selective oxidation of sulfides to sulfoxides and sulfones

A green, efficient and selective approach for the oxidation of sulfides to sulfoxides and sulfones with H2O2 at room temperature is reported. The reaction is performed in the presence of tungstophosphoric acid (PW12) supported on an aluminum incorporated mesocellulous silica foam (Al-MCF) (via both: the impregnation and encapsulation methods), as heterogeneous and reusable catalysts. The structural and textural characterizations of these catalysts were done using FTIR, X-ray diffraction, N2 adsorption-desorption and TEM.

TAPC-promoted oxidation of sulfides and deoxygenation of sulfoxides

Figure presented. 1,3,5-Triazo-2,4,6-triphosphorine-2,2,4,4,6,6- tetrachloride (TAPC) was found to be an efficient promoter for the oxidation of sulfides and deoxygenation of sulfoxides. Excellent yields, short reaction time, easy and quick isolation of the products, solvent-free process, and excellent chemoselectivity are the main advantages of this procedure.