100959-19-1

Basic information

• Product Name: 4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE
• Synonyms: HEXAHYDRO-P-TOLUIDINE HYDROCHLORIDE;4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE;4-METHYLCYCOHEXYLAMINE HYDROCHLORIDE;1-Amino-4-methylcyclohexane hydrochloride;4-MethylcyclohexylamineHCl;4-methylcyclohexylamine hydrochloride, cis + trans;4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE 98+%;4-Methylcyclohexylamine hydrochloride, cis + trans, 98+%
• CAS NO: 100959-19-1
• Molecular Formula: C₇H₁₅N*ClH
• Molecular Weight: 149.66
• EINECS: -0
• Mol File: 100959-19-1.mol

Chemical Properties

• Melting Point: 224°C (dec.)
• Boiling Point: 195.9°C at 760 mmHg
• Flash Point: 72.3°C
• Appearance: /
• Vapor Pressure: 0.347mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Hygroscopic
• BRN: 3670820
• CAS DataBase Reference: 4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE(100959-19-1)
• EPA Substance Registry System: 4-METHYLCYCLOHEXYLAMINE HYDROCHLORIDE(100959-19-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 100959-19-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Industry:
4-Methylcyclohexylamine Hydrochloride is used as a reagent for various chemical reactions and syntheses, contributing to the production of different compounds and materials.
Used in Research Applications:
4-Methylcyclohexylamine Hydrochloride is used as a catalyst in research settings, facilitating specific chemical reactions and aiding in the discovery of new compounds and processes.

InChI:InChI=1/C7H15N.ClH/c1-6-2-4-7(8)5-3-6;/h6-7H,2-5,8H2,1H3;1H

Upstream product

• 4994-13-2 4-methylcyclohexanone oxime 

Downstream Products

• 311346-54-0 N-(trans-4-methylcyclohexyl)isoquinoline-1-carboxamide 
• 311346-55-1 N-(trans-4-methylcyclohexyl)isoquinoline-3-carboxamide 
• 311347-24-7 N-(trans-4-methylcyclohexyl)-6-fluoroquinoxaline-2-carboxamide 
• 311346-52-8 N-(trans-4-methylcyclohexyl)quinoline-4-carboxamide 
• 311347-13-4 N-(trans-4-methylcyclohexyl)-7-methoxyquinoline-3-carboxamide 
• 311347-34-9 N-(trans-4-methylcyclohexyl)-8-methoxyquinoline-3-carboxamide 
• 311347-16-7 N-(trans-4-methylcyclohexyl)-6-fluoroquinoline-3-carboxamide 
• 311347-17-8 N-(trans-4-methylcyclohexyl)-8-fluoroquinoline-3-carboxamide 
• 31715-95-4 N-(trans-4-methylcyclohexyl)-2-dimethylaminoacetamide 
• 147906-05-6 N-(trans-4-methylcyclohexyl)-4-dimethylaminobutylamide 
• 33483-65-7 trans-4-methylcyclohexylamine hydrochloride 
• 760989-17-1 N-[(3-iodo-1,4-dihydroindeno[1,2-c]pyrazol-6-yl)methyl]-N-(trans-4-methylcyclohexyl) amine 

Relevant articles and documents

A NOVEL PROCESS FOR PREPARATION OF SUBSTANTIALLY PURE GLIMEPIRIDE

The present invention discloses a novel process for purification of trans-4-methyl cyclohexylamine HC1 and 4-[2-(3-Ethyl-4-methyl-2-carbonyl pyrrolidine amido) ethyl] benzene sulfonamide used in the synthesis of 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methyl cyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide(I), popularly known as Glimepiride. The present invention also discloses a novel purification of Glimepiride Form I (I), having the undesired cis isomer below 0.15%. Glimepiride (I) is useful in the treatment of diabetes mellitus.

Compound and use of the same as medicine

Disclosed herein is a specific cinnamic acid derivative such as methyl 4-(4-acetoxy-3-methoxycinnamanide)-1-cyclohexanecarboxylate, or a pharmaceutically acceptable salt thereof. These compounds are useful as IV-type allergic reaction-suppressive drugs.