101079-64-5

Basic information

• Product Name: 5-BROMO-3-NITRO-THIOPHENE-2-CARBOXYLIC ACID
• Synonyms: 5-BROMO-3-NITRO-THIOPHENE-2-CARBOXYLIC ACID;5-bromo-3-nitro-2-Thiophenecarboxylic acid;2-Thiophenecarboxylic acid, 5-bromo-3-nitro-
• CAS NO: 101079-64-5
• Molecular Formula: C₅H₂BrNO₄S
• Molecular Weight: 252.04268
• Mol File: 101079-64-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BROMO-3-NITRO-THIOPHENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-3-NITRO-THIOPHENE-2-CARBOXYLIC ACID(101079-64-5)
• EPA Substance Registry System: 5-BROMO-3-NITRO-THIOPHENE-2-CARBOXYLIC ACID(101079-64-5)

Safety Data

• Hazardous Substances Data: 101079-64-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-3-nitro-thiophene-2-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its anti-inflammatory, anti-bacterial, and anti-cancer properties. Its unique structure allows it to be incorporated into drug molecules, enhancing their therapeutic effects and targeting specific biological pathways.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Bromo-3-nitro-thiophene-2-carboxylic acid is utilized as a building block for the development of new agrochemicals. Its chemical properties make it suitable for the creation of compounds with pesticidal or herbicidal activities, contributing to more effective crop protection strategies.
Used in Organic Synthesis:
5-Bromo-3-nitro-thiophene-2-carboxylic acid is used as a versatile building block in organic synthesis for the production of complex molecules. Its reactivity and structural features enable the synthesis of a wide range of organic compounds, including specialty chemicals, dyes, and other materials with specific applications in various industries.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 5-Bromo-3-nitro-thiophene-2-carboxylic acid is employed as a starting material for the development of new drugs and drug candidates. Its diverse biological activities and potential to modulate various signaling pathways make it a promising candidate for the treatment of various diseases and conditions.
Used in Chemical Intermediates:
5-Bromo-3-nitro-thiophene-2-carboxylic acid is used as a chemical intermediate in the synthesis of other organic compounds. Its unique structure and reactivity make it a valuable component in the production of various specialty chemicals, contributing to the development of new materials and technologies.

Upstream product

• 75735-44-3 Methyl 3-nitrothiophene-2-carboxylate 
• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 
• 99839-45-9 methyl 5-bromo-3-nitrothiophene-2-carboxylate 

Downstream Products

• 515141-51-2 GW803430 
• 947176-22-9 3-amino-5-bromothiophene-2-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-ylethoxy)-phenyl]amide 
• 515141-49-8 6-bromo-3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one 
• 515141-48-7 5-bromo-3-nitro-thiophene-2-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amide 

Relevant articles and documents

NOVEL 2,3,5-SUBSTITUTED THIOPHENE COMPOUND AS PROTEIN KINASE INHIBITOR

The present invention relates to a novel 2,3,5-substituted thiophene compound having inhibitory activity against kinases, an anticancer agent including the compound as an active ingredient, and a method for preparing the compound.

NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

The invention relates to amino alcohol-substituted arylthienopyrimidinones and their derivatives, and their physiologically tolerated salts and physiologically functional derivatives, their preparation, medicaments comprising at least one amino alcohol-su