A series of 4-alkyl-1,3-dihydro-5--2H-imidazol-2-ones 9 was synthesized and evaluated in vitro for positive inotropic and cyclic AMP phosphodiesterase inhibitory activity.A wide range of inotropic and enzyme-inhibitory potencies wa
Hagedorn, Alfred A.,Erhardt, Paul W.,Lumma, William C.,Wohl, Ronald, A.,Cantor, Elinor,et al.
Novel imidazolonecarbonylarylimidazoles of the formula: STR1 are described having cardiovascular properties, especially as cardiotonic agents in the treatment of congestive heart failure. Pharmaceutical formulations containing such compounds are also prov
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(2008/06/13)
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