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1-(2-(Phenanthren-9-yl)phenyl)propan-2-one is a chemical compound that serves as a metabolite of Dibenzo[def,p]chrysene (D416945), a potent tumorigen and polycyclic aromatic hydrocarbon found in hot mix asphalt paving workers.

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  • 1013933-56-6 Structure
  • Basic information

    1. Product Name: 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one
    2. Synonyms: 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one;1-[2-(9-Phenanthrenyl)phenyl]-2-propanone;RPVQGHQWVSHLPY-UHFFFAOYSA-N
    3. CAS NO:1013933-56-6
    4. Molecular Formula: C23H18O
    5. Molecular Weight: 310.38842
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1013933-56-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 489.6±24.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.152±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: DCM, Ethyl Acetate
    9. CAS DataBase Reference: 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one(1013933-56-6)
    11. EPA Substance Registry System: 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one(1013933-56-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1013933-56-6(Hazardous Substances Data)

1013933-56-6 Usage

Uses

1. Used in Research Applications:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one is used as a research compound for studying the metabolic pathways and effects of Dibenzo[def,p]chrysene, a potent tumorigen, on human health and the environment.
2. Used in Environmental and Occupational Health:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one is used as a biomarker to monitor the exposure of hot mix asphalt paving workers to Dibenzo[def,p]chrysene and other polycyclic aromatic hydrocarbons, which can help in assessing the health risks associated with their occupation.
3. Used in Pharmaceutical Development:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one may be used as a starting point for the development of new drugs or therapies targeting the metabolic pathways of Dibenzo[def,p]chrysene and other related tumorigenic compounds.
4. Used in Analytical Chemistry:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one can be employed as a reference compound in the development and validation of analytical methods for the detection and quantification of Dibenzo[def,p]chrysene and other polycyclic aromatic hydrocarbons in environmental and biological samples.
5. Used in Toxicology Studies:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one can be utilized in toxicological research to investigate the toxic effects of Dibenzo[def,p]chrysene and its metabolites on various biological systems, which may contribute to a better understanding of the mechanisms underlying their tumorigenic properties.

Check Digit Verification of cas no

The CAS Registry Mumber 1013933-56-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,3,9,3 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1013933-56:
(9*1)+(8*0)+(7*1)+(6*3)+(5*9)+(4*3)+(3*3)+(2*5)+(1*6)=116
116 % 10 = 6
So 1013933-56-6 is a valid CAS Registry Number.

1013933-56-6Downstream Products

1013933-56-6Relevant articles and documents

Synthesis of dibenzo[def,p]chrysene, its active metabolites, and their 13C-labeled analogues

Xu, Daiwang,Duan, Yazhen,Blair, Ian A.,Penning, Trevor M.,Harvey, Ronald G.

supporting information; experimental part, p. 1059 - 1062 (2009/04/06)

Dibenzo[def,p]chrysene (DBC) Is a highly carcinogenic polycyclic aromatic hydrocarbon suspected to be Involved in initiation of lung cancer in smokers. Efficient new syntheses of DBC, Its active metabolites [DBC diol (1), DBC dione (2), DBC diol epoxlde (3)], and their previously unknown 13C 2-labeled analogues are reported. The 13C 2-labeled analogues are required as standards for sensitive methods of analysis of their DNA adducts in human cells using stable isotope dilution liquid chromatography/tandem mass spectrometry.

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