1013933-56-6 Usage
Uses
1. Used in Research Applications:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one is used as a research compound for studying the metabolic pathways and effects of Dibenzo[def,p]chrysene, a potent tumorigen, on human health and the environment.
2. Used in Environmental and Occupational Health:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one is used as a biomarker to monitor the exposure of hot mix asphalt paving workers to Dibenzo[def,p]chrysene and other polycyclic aromatic hydrocarbons, which can help in assessing the health risks associated with their occupation.
3. Used in Pharmaceutical Development:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one may be used as a starting point for the development of new drugs or therapies targeting the metabolic pathways of Dibenzo[def,p]chrysene and other related tumorigenic compounds.
4. Used in Analytical Chemistry:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one can be employed as a reference compound in the development and validation of analytical methods for the detection and quantification of Dibenzo[def,p]chrysene and other polycyclic aromatic hydrocarbons in environmental and biological samples.
5. Used in Toxicology Studies:
1-(2-(Phenanthren-9-yl)phenyl)propan-2-one can be utilized in toxicological research to investigate the toxic effects of Dibenzo[def,p]chrysene and its metabolites on various biological systems, which may contribute to a better understanding of the mechanisms underlying their tumorigenic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1013933-56-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,3,9,3 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1013933-56:
(9*1)+(8*0)+(7*1)+(6*3)+(5*9)+(4*3)+(3*3)+(2*5)+(1*6)=116
116 % 10 = 6
So 1013933-56-6 is a valid CAS Registry Number.
1013933-56-6Relevant articles and documents
Synthesis of dibenzo[def,p]chrysene, its active metabolites, and their 13C-labeled analogues
Xu, Daiwang,Duan, Yazhen,Blair, Ian A.,Penning, Trevor M.,Harvey, Ronald G.
supporting information; experimental part, p. 1059 - 1062 (2009/04/06)
Dibenzo[def,p]chrysene (DBC) Is a highly carcinogenic polycyclic aromatic hydrocarbon suspected to be Involved in initiation of lung cancer in smokers. Efficient new syntheses of DBC, Its active metabolites [DBC diol (1), DBC dione (2), DBC diol epoxlde (3)], and their previously unknown 13C 2-labeled analogues are reported. The 13C 2-labeled analogues are required as standards for sensitive methods of analysis of their DNA adducts in human cells using stable isotope dilution liquid chromatography/tandem mass spectrometry.