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CAS

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10147-05-4

2-(quinolin-4-yl)acetamide, also known as quinaldine acetamide, is a synthetic chemical compound derived from quinoline, a heterocyclic aromatic organic compound. It possesses the molecular formula C11H10N2O and is recognized for its potential medicinal properties. 2-(quinolin-4-yl)acetamide has been demonstrated to exhibit anticonvulsant and neuroprotective effects in animal studies, positioning it as a promising candidate for the development of new drugs aimed at treating neurological disorders. Furthermore, 2-(quinolin-4-yl)acetamide is considered to be a relatively safe chemical with low toxicity levels, which adds to its appeal in pharmaceutical research and development.

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  • 10147-05-4 Structure

  • Basic information

    1. Product Name: 2-(quinolin-4-yl)acetamide
    2. Synonyms: 2-(quinolin-4-yl)acetamide
    3. CAS NO:10147-05-4
    4. Molecular Formula: C11H10 N2 O
    5. Molecular Weight: 186.21
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 10147-05-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(quinolin-4-yl)acetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(quinolin-4-yl)acetamide(10147-05-4)
    11. EPA Substance Registry System: 2-(quinolin-4-yl)acetamide(10147-05-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 10147-05-4(Hazardous Substances Data)

10147-05-4 Usage

Uses

Used in Pharmaceutical Research:
2-(quinolin-4-yl)acetamide is utilized as a building block in organic synthesis and pharmaceutical research, serving as a key component in the development of new drugs. Its demonstrated anticonvulsant and neuroprotective effects make it a valuable asset in the search for novel treatments for neurological disorders.
Used in Drug Development for Neurological Disorders:
2-(quinolin-4-yl)acetamide is employed as a potential candidate for the development of new drugs for the treatment of neurological disorders. Its efficacy in animal studies, where it has shown to possess anticonvulsant and neuroprotective properties, suggests that it could play a significant role in the creation of therapeutics for conditions such as epilepsy and neurodegenerative diseases.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(quinolin-4-yl)acetamide is used as a versatile building block. Its chemical structure allows for the creation of a variety of complex molecules, making it an essential tool in the synthesis of a wide range of organic compounds. This utility extends to various industries, including pharmaceuticals, where it can contribute to the development of innovative chemical entities.

Check Digit Verification of cas no

The CAS Registry Mumber 10147-05-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,4 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10147-05:
(7*1)+(6*0)+(5*1)+(4*4)+(3*7)+(2*0)+(1*5)=54
54 % 10 = 4
So 10147-05-4 is a valid CAS Registry Number.

10147-05-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-quinolin-4-ylacetamide

1.2 Other means of identification

Product number -
Other names 2-quinolin-4-yl-acetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10147-05-4 SDS

10147-05-4Downstream Products

10147-05-4Relevant articles and documents

Aryl-indolyl maleimides as inhibitors of CaMKIIδ. Part 1: SAR of the aryl region

Levy, Daniel E.,Wang, Dan-Xiong,Lu, Qing,Chen, Zheng,Perumattam, John,Xu, Yong-jin,Liclican, Albert,Higaki, Jeffrey,Dong, Hanmin,Laney, Maureen,Mavunkel, Babu,Dugar, Sundeep

, p. 2390 - 2394 (2008/09/21)

A family of aryl-substituted maleimides was prepared and studied for their activity against calmodulin dependant kinase. Inhibitory activities against the enzyme ranged from 34 nM to >20 μM and were dependant upon both the nature of the aryl group and the hydrogen bond donating potential of the maleimide ring. Key interactions with the kinase ATP site and hinge region were found to be consistent with homology modeling predictions.

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