101774-27-0

Basic information

• Product Name: 6-Bromoindole-3-carboxylic acid
• Synonyms: 6-BROMO-1H-INDOLE-3-CARBOXYLIC ACID;6-BROMO-1-(TERT-BUTOXYCARBONYL)-1H-INDOLE-3-CARBOXYLIC ACID;6-bromoindole-3-carboxylic acid;6-bromo-1H-indole-3-carboxylic;7024 6-BROMO-1H-INDOLE-3-CARBOXYLIC ACID;1H-Indole-3-carboxylic acid, 6-broMo-;6-broMo-3-indole acid
• CAS NO: 101774-27-0
• Molecular Formula: C₉H₆BrNO₂
• Molecular Weight: 240.05
• Product Categories: Indole
• Mol File: 101774-27-0.mol

Chemical Properties

• Melting Point: 212 °C
• Boiling Point: 470.932 °C at 760 mmHg
• Flash Point: 238.611 °C
• Appearance: /
• Density: 1.838 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.749
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.61±0.10(Predicted)
• CAS DataBase Reference: 6-Bromoindole-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromoindole-3-carboxylic acid(101774-27-0)
• EPA Substance Registry System: 6-Bromoindole-3-carboxylic acid(101774-27-0)

Safety Data

• Hazardous Substances Data: 101774-27-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
6-Bromoindole-3-carboxylic acid is used as a starting material for the synthesis of various biologically active molecules, contributing to the development of new organic compounds with potential applications in different fields.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 6-Bromoindole-3-carboxylic acid is utilized as a building block for the preparation of pharmaceutical compounds. Its unique structure and functional groups offer a foundation for the creation of new drugs or drug candidates, potentially leading to advancements in medicinal chemistry.
Used in Medicinal Chemistry Research:
6-Bromoindole-3-carboxylic acid is employed in medicinal chemistry research to explore its potential medicinal and pharmacological properties. This exploration can facilitate the discovery of new therapeutic agents or enhance the understanding of existing drug mechanisms.

InChI:InChI=1/C9H6BrNO2/c10-5-1-2-6-7(9(12)13)4-11-8(6)3-5/h1-4,11H,(H,12,13)

Downstream Products

• 868656-97-7 6-bromo-1H-indole-3-carboxylic acid methyl ester 
• 573716-94-6 6-bromo-1-cyanomethyl-1H-indole-3-carboxylic acid 
• 1296199-37-5 N-(3-methoxybenzyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296201-93-8 C₁₇H₁₅BrN₂O₂ 
• 1296199-41-1 N-(2-methoxybenzyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296199-42-2 N-(4-methoxybenzyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296199-43-3 6-(1H-pyrazol-4-yl)-N-(3-(trifluoromethoxy)benzyl)-1H-indole-3-carboxamide 
• 1296199-48-8 N-(3,4-difluorobenzyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296199-38-6 (R)-N-(1-(3-methoxyphenyl)ethyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296199-39-7 (S)-N-(1-(3-methoxyphenyl)ethyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296199-46-6 N-(cyclohexylmethyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296199-45-5 N-(3-methoxyphenethyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296199-49-9 N-(2,5-dimethoxybenzyl)-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide 
• 1296202-05-5 C₁₈H₁₇BrN₂O₃ 

Relevant articles and documents

New amino acid derivatives from the marine ascidian Leptoclinides dubius

From the cytotoxic extracts of the marine ascidian Leptoclinides dubius, N-(p-hydroxybenzoyl)L-arginine (1), N-(1H-indolyl-3-carbonyl)-D-arginine (2), and N-(6-bromo-1H-indolyl-3-carbonyl)-R, where R is L-Arg (4), L-His (5), and the very rare amino acid L-enduracididine (3), have been isolated and identified by spectroscopic data, hydrolysis, and comparison with authentic samples.