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2-AMino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 2-Amino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester

    Cas No: 1019108-35-0

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  • 2-amino-5,6-dihydro-4H-cyclopentathiazole-4-carboxylic acid ethyl ester; ethyl 2-amino-5,6-dihydro-4H-cyclopenta[α][1,3]thiazole-4-carboxylate; cas no. 1019108-35-0 97%

    Cas No: 1019108-35-0

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  • 1019108-35-0 Structure
  • Basic information

    1. Product Name: 2-AMino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester
    2. Synonyms: Ethyl 2-aMino-5,6-dihydro-4H-cyclopenta[d]thiazole-4-carboxylate
    3. CAS NO:1019108-35-0
    4. Molecular Formula: C10H14N2O2S
    5. Molecular Weight: 226.29536
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1019108-35-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 358.9±30.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.346±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 5.07±0.40(Predicted)
    10. CAS DataBase Reference: 2-AMino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-AMino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester(1019108-35-0)
    12. EPA Substance Registry System: 2-AMino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester(1019108-35-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1019108-35-0(Hazardous Substances Data)

1019108-35-0 Usage

Chemical compound

2-Amino-4,5,6,7-tetrahydro-benzothiazole-4-carboxylic acid ethyl ester

Derivative of

Benzothiazole-4-carboxylic acid

Functional groups

Amino group, carboxylic acid group

Uses

Pharmaceutical research, drug development, synthesis of potential drug candidates and bioactive molecules

Other potential applications

Chemical biology, medicinal chemistry

Versatility

Can be utilized as a building block in various fields of science and technology

Check Digit Verification of cas no

The CAS Registry Mumber 1019108-35-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,9,1,0 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1019108-35:
(9*1)+(8*0)+(7*1)+(6*9)+(5*1)+(4*0)+(3*8)+(2*3)+(1*5)=110
110 % 10 = 0
So 1019108-35-0 is a valid CAS Registry Number.

1019108-35-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-amino-5,6-dihydro-4H-cyclopenta[d]thiazole-4-carboxylate

1.2 Other means of identification

Product number -
Other names ethyl 2-amino-5,6-dihydro-4H-cyclopenta[d][1,3]thiazole-4-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1019108-35-0 SDS

1019108-35-0Relevant articles and documents

THIAZOLOPYRIMIDINONES AS MODULATORS OF NMDA RECEPTOR ACTIVITY

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, (2015/04/28)

The present invention relates to certain thiazolopyrimidinone compounds for use in modulating NMDA receptor activity, pharmaceutical compositions comprising such compounds and methods of treating neurological and psychiatric conditions.

Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder

Moyes, Christopher R.,Berger, Richard,Goble, Stephen D.,Harper, Bart,Shen, Dong-Ming,Wang, Liping,Bansal, Alka,Brown, Patricia N.,Chen, Airu S.,Dingley, Karen H.,Di Salvo, Jerry,Fitzmaurice, Aileen,Gichuru, Loise N.,Hurley, Amanda L.,Jochnowitz, Nina,Miller, Randall R.,Mistry, Shruty,Nagabukuro, Hiroshi,Salituro, Gino M.,Sanfiz, Anthony,Stevenson, Andra S.,Villa, Katherine,Zamlynny, Beata,Struthers, Mary,Weber, Ann E.,Edmondson, Scott D.

, p. 1437 - 1453 (2014/03/21)

A series of conformationally restricted acetanilides were synthesized and evaluated as β3-adrenergic receptor agonists (β3-AR) for the treatment of overactive bladder (OAB). Optimization studies identified a five-membered ring as the preferred conformational lock of the acetanilide. Further optimization of both the aromatic and thiazole regions led to compounds such as 19 and 29, which have a good balance of potency and selectivity. These compounds have significantly reduced intrinsic clearance compared to our initial series of pyridylethanolamine β3-AR agonists and thus have improved unbound drug exposures. Both analogues demonstrated dose dependent β3-AR mediated responses in a rat bladder hyperactivity model.

COMBINATION THERAPY USING A BETA 3 ADRENERGIC RECEPTOR AGONIST AND AN ANTIMUSCARINIC AGENT

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Page/Page column 27, (2011/04/26)

Described herein is an improved method of treating overactive bladder, wherein the method comprises administering to a patient in need thereof a beta 3 adrenergic receptor agonist, an antimuscarinic agent, and an optional selective M2 antagonist. Such combination therapy provides improved efficacy and/or reduced side effects.

HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS

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Page/Page column 34, (2009/10/30)

The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.

HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS

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Page/Page column 29, (2009/10/17)

The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.

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